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. 2020 Nov 19;20(1):1742.
doi: 10.1186/s12889-020-09826-8.

COVID-19 mortality risk for older men and women

N David Yanez  1 , Noel S Weiss  2 , Jacques-André Romand  3 , Miriam M Treggiari  4
Affiliations

COVID-19 mortality risk for older men and women

N David Yanez et al. BMC Public Health. .

Abstract

Background: Case-fatality from COVID-19 has been reported to be relatively high in patients age 65 years or older. We sought to determine the age-specific rates of COVID-19 mortality at the population level.

Methods: We obtained information regarding the total number of COVID-19 reported deaths for six consecutive weeks beginning at the 50th recorded death, among 16 countries that reported a relatively high number of COVID-19 cases as of April 12, 2020. We performed an ecological study to model COVID-19 mortality rates per week by age group (54 years or younger, 55-64 years, and 65 years or older) and sex using a Poisson mixed effects regression model.

Results: Over the six-week period of data, there were 178,568 COVID-19 deaths from a total population of approximately 2.4 billion people. Age and sex were associated with COVID-19 mortality. Compared with individuals ages 54 years or younger, the incident rate ratio (IRR) was 8.1, indicating that the mortality rate of COVID-19 was 8.1 times higher (95%CI = 7.7, 8.5) among those 55 to 64 years, and more than 62 times higher (IRR = 62.1; 95%CI = 59.7, 64.7) among those ages 65 or older. Mortality rates from COVID-19 were 77% higher in men than in women (IRR = 1.77, 95%CI = 1.74, 1.79).

Conclusions: In the 16 countries examined, persons age 65 years or older had strikingly higher COVID-19 mortality rates compared to younger individuals, and men had a higher risk of COVID-19 death than women.

Keywords: Age; Pandemic; Population health; Severe acute respiratory syndrome-CoronaVirus-2, epidemiology.

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Conflict of interest statement

The authors declare they have no competing interests.

Figures

Fig. 1
Fig. 1
COVID-19 actual and estimated average number of weekly deaths for six consecutive weeks beginning with the 50th recorded death, among 16 countries that reported a relatively high number of COVID-19 cases as of April 12, 2020. Part A women, Part B men
Fig. 2
Fig. 2
COVID-19 actual and estimated weekly death rates for six consecutive weeks beginning with the 50th recorded death, among 16 countries that reported a relatively high number of COVID-19 cases as of April 12, 2020. Part A women, Part B men
See this image and copyright information in PMC

References

    1. Organization WH . World Health Organization Coronavirus Disease (COVID-2019) Situation Report - 91. Coronavirus disease (COVID-2019) situation reports Web site. 2020.
    1. Porcheddu R, Serra C, Kelvin D, Kelvin N, Rubino S. Similarity in case fatality rates (CFR) of COVID-19/SARS-COV-2 in Italy and China. J Infect Dev Ctries. 2020;14(2):125–128. doi: 10.3855/jidc.12600. - DOI - PubMed
    1. Grasselli G, Zangrillo A, Zanella A, Antonelli M, Cabrini L, Castelli A, Cereda D, Coluccello A, Foti G, Fumagalli R, Iotti G, Latronico N, Lorini L, Merler S, Natalini G, Piatti A, Ranieri MV, Scandroglio AM, Storti E, Cecconi M, Pesenti A. COVID-19 Lombardy ICU Network. Baseline characteristics and outcomes of 1591 patients infected with SARS-CoV-2 admitted to ICUs of the Lombardy region, Italy. JAMA. 2020;323(16):1574–81. 10.1001/jama.2020.5394. - PMC - PubMed
    1. Univeristy JH. Center for Systems Science and Engineering Coronavirus Resource Center. 2020.
    1. CIA . The World Factbook. 2020.

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