Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2021 Aug;42(8):997-1000.
doi: 10.1017/ice.2020.1335. Epub 2020 Nov 20.

The impact of coronavirus disease 2019 (COVID-19) response on central-line-associated bloodstream infections and blood culture contamination rates at a tertiary-care center in the Greater Detroit area

Jennifer LeRose  1 , Avnish Sandhu  2 , Jordan Polistico  2 , Joe Ellsworth  3 , Mara Cranis  3 , Lavina Jabbo  3 , Lori Cullen  3 , Judy Moshos  3 , Lobelia Samavati  4 , Teena Chopra  2
Affiliations

The impact of coronavirus disease 2019 (COVID-19) response on central-line-associated bloodstream infections and blood culture contamination rates at a tertiary-care center in the Greater Detroit area

Jennifer LeRose et al. Infect Control Hosp Epidemiol. 2021 Aug.

Abstract

We conducted a comparative retrospective study to quantify the impact of coronavirus disease 2019 (COVID-19) on patient safety. We found a statistically significant increase in central-line-associated bloodstream infections and blood culture contamination rates during the pandemic. Increased length of stay and mortality were also observed during the COVID-19 pandemic.

PubMed Disclaimer

Figures

Fig. 1.
Fig. 1.
Central-line–associated bloodstream infections per 1,000 central-line days between January through May. The pre–COVID-19 cohort had 6 central-line bloodstream infections (CLABSIs) per 15,026 central-line days, and the COVID-19 cohort had 30 CLABSIs per 18,106 central-line days. The change in the CLABSI rate was statistically significant at P < .05.
See this image and copyright information in PMC

References

    1. Haddadin Y, Annamaraju P, Regunath H. Central-line–associated blood stream infections (CLABSIs). NCBI Resources website. https://www.ncbi.nlm.nih.gov/books/NBK430891/. Published 2020. Accessed July 25, 2020, 2020.
    1. Furuya EY, Dick AW, Herzig CTA, Pogorzelska-Maziarz M. Central-line–associated bloodstream infection reduction and bundle compliance in intensive care units: a national study. Infect Control Hosp Epidemiol 2016;37:805–810. - PMC - PubMed
    1. O’Grady N, Alexander M, Dellinger PE, et al. Guidelines for the prevention of intravascular catheter related infections. Clin Infect Dis 2011;52:162–193. - PMC - PubMed
    1. Adalja AA, Toner E, Inglesby TV. Priorities for the US health community responding to COVID-19. JAMA 2020;323:1343–1344. - PubMed
    1. National Healthcare Safety Network (NHSN) Patient Safety Component Manual. Centers for Disease Control and Prevention website. https://www.cdc.gov/nhsn/pdfs/pscmanual/pcsmanual_current.pdf. Published 2020. Accessed September 15, 2020.