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. 2020 Dec 31;39(4):501-503.
doi: 10.23876/j.krcp.20.116.

Decline in platelet function following administration of a snake venom-derived hemocoagulase in a patient with end-stage renal disease

Byung Soo Kang  1 , Young Il Kim  1 , Sae-Yong Hong  1 , Seong Su Ban  2 , Won Seon Han  3 , Byung Geun Kim  4
Affiliations

Decline in platelet function following administration of a snake venom-derived hemocoagulase in a patient with end-stage renal disease

Byung Soo Kang et al. Kidney Res Clin Pract. .
No abstract available

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Conflict of interest statement

Conflicts of interest

All authors have no conflicts of interest to declare.

Figures

Figure 1
Figure 1. Sequential measurements of the platelet aggregation function test in case 1.
Botropase is initiated on two separate occasions. First, botropase 4 mL/day for three days after the surgery as usual. No platelet function test was performed during this period. Second, botropase initiated between hospitalization days 6 and 11 to treat gastric ulcer bleeding. The platelet function test was performed four times on hospitalization days 11, 12, 13, and 16. ADP, adenosine diphosphate; AUC, area under the aggregation curve; U, units.
Figure 2
Figure 2. Sequential measurements of the platelet aggregation function test in case 2.
The platelet function test was performed on hospitalization days 1, 3, 4, and 6. Botropase-mediated platelet dysfunction developed within three days after injection and recovered within two days after cessation. ADP, adenosine diphosphate; AUC, area under the aggregation curve; U, units.
See this image and copyright information in PMC

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