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Comment
. 2020 Nov 19;80(4):560-561.
doi: 10.1016/j.molcel.2020.10.044.

Bridging a DNA Break to Leave a Poly(ADP-Ribose) Mark on Chromatin

Élise Rouleau-Turcotte  1 , John M Pascal  2
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Bridging a DNA Break to Leave a Poly(ADP-Ribose) Mark on Chromatin

Élise Rouleau-Turcotte et al. Mol Cell. .
Free article

Abstract

Bilokapic at al. (2020) capture PARP2 and its accessory factor HPF1 bridging a DNA break between two nucleosomes, providing a captivating view of the context in which PARP2/HPF1 employ ADP-ribose protein modification to coordinate DNA repair and alter chromatin structure.

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