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Editorial
. 2021 Apr;128(4):490-493.
doi: 10.1016/j.ophtha.2020.10.008. Epub 2020 Nov 17.

Updating the Staging System for Diabetic Retinal Disease

Jennifer K Sun, Lloyd Paul Aiello, Michael D Abràmoff, David A Antonetti, Sanjoy Dutta, Marlon Pragnell, S Robert Levine, Thomas W Gardner
Editorial

Updating the Staging System for Diabetic Retinal Disease

Jennifer K Sun et al. Ophthalmology. 2021 Apr.
No abstract available

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Conflict of interest statement

Conflict of Interest: (In addition to ICMJE forms uploaded) MDA: Digital Diagnostics Investor, Director, Employee, Patents and Patent Applications.

Figures

Figure 1.
Figure 1.
Schematic demonstrating relationships between retinal neural and vascular pathology with visual function for consideration in a revised severity scale for diabetic retinal disease. Background shading represents the context of systemic health status including, but not limited to variables such as glycemic control, blood pressure, lipids and the presence of comorbidities. (A) represents an eye with excellent vision and minimal to mild retinal neural or vascular abnormalities in a patient with good systemic health. (B) is an eye with moderate vision loss, e.g. from diabetic macular edema, and combined neurovascular disease in an individual with some systemic health issues. (C) represents an eye with late stage disease, e.g. from a macular traction retinal detachment, and severe vision loss in a patient with poor overall systemic health.
See this image and copyright information in PMC

References

    1. Early Treatment Diabetic Retinopathy Study Research Group. Grading diabetic retinopathy from stereoscopic color fundus photographs - an extension of the modified Airlie House classification: ETDRS report number 10. Ophthalmology. 2020;127(4S):S99–S119. - PubMed
    1. Wilkinson CP, Ferris FL 3rd, Klein RE, et al.Proposed international clinical diabetic retinopathy and diabetic macular edema disease severity scales. Ophthalmology. 2003;110(9):1677–1682. - PubMed
    1. Abràmoff MD, Fort PE, Han IC, et al.Approach for a clinically useful comprehensive classification of vascular and neural aspects of diabetic retinal disease. Invest Ophthalmol Vis Sci. 2018;59(1):519–527. - PMC - PubMed
    1. Aiello LP, Odia I, Glassman AR, et al.; Diabetic Retinopathy Clinical Research Network. Comparison of Early Treatment Diabetic Retinopathy Study standard 7-field imaging with ultrawide-field imaging for determining severity of diabetic retinopathy. JAMA Ophthalmol. 2019January1;137(1):65–73. - PMC - PubMed
    1. Abràmoff MD, Lavin PT, Birch M, et al.Pivotal trial of an autonomous AI-based diagnostic system for detection of diabetic retinopathy in primary care offices. Nature Digital Medicine. 2018;1(1):39. - PMC - PubMed

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