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Review
. 2021 Jun;37(6):2105-2113.
doi: 10.1007/s00381-020-04970-3. Epub 2020 Nov 20.

Effects of systemic corticosteroid treatment on pseudotumoral hemicerebellitis: a case report and literature review

Amirti Vivekanandan  1 , Brendan Santyr  2 , Adrianna Ranger  2   3
Affiliations
Review

Effects of systemic corticosteroid treatment on pseudotumoral hemicerebellitis: a case report and literature review

Amirti Vivekanandan et al. Childs Nerv Syst. 2021 Jun.

Abstract

Purpose: Pseudotumoral hemicerebellitis is an acute, unilateral inflammation of the cerebellum that typically affects the pediatric population. The purpose of this paper is to review cases of pseudotumoral hemicerebellitis in the literature and evaluate if treatment with systemic corticosteroids reduces length of time to symptomatic recovery.

Methods: We present a case report of a 12-year-old male with pseudotumoral hemicerebellitis and unilateral cerebellar dysfunction. Additionally, we review the thirty-five reported cases of pseudotumoral hemicerebellitis with respect to length of time to symptomatic recovery with or without systemic corticosteroid treatment.

Results: Thirty cases reported length of time to symptomatic recovery. Including our case, the mean time to recovery for those treated with systemic corticosteroids (n = 20) was 48.05 days (SE = 16.3). The mean time to recovery for those treated without (n = 10) was 86.7 days (SE = 29.3).

Conclusions: Treatment with systemic corticosteroids was associated with a faster time to symptomatic recovery compared to without. Regardless of etiology, reducing inflammation and mass effect involved in pseudotumoral hemicerebellitis may be integral to a more rapid return to neurological baseline.

Keywords: Corticosteroids; MRI; Pediatric; Pseudotumoral hemicerebellitis.

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References

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