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Clinical Trial
. 1987 Dec;117(6):751-8.
doi: 10.1111/j.1365-2133.1987.tb07356.x.

The effect of captopril on cutaneous blood flow in patients with primary Raynaud's phenomenon

M H Rustin  1 , N E Almond, J A Beacham, R J Brooks, D P Jones, E D Cooke, P M Dowd
Affiliations
Clinical Trial

The effect of captopril on cutaneous blood flow in patients with primary Raynaud's phenomenon

M H Rustin et al. Br J Dermatol. 1987 Dec.

Abstract

Fifteen patients with primary Raynaud's phenomenon received captopril 25 mg or placebo, three times daily for 6 weeks, in a randomized double-blind cross-over study. Compared with placebo, captopril produced a significant improvement in cutaneous blood flow but did not alter the frequency or severity of attacks of Raynaud's phenomenon.

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