Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2020 Jul-Aug;23(4):449-457.
doi: 10.4103/aian.AIAN_27_20. Epub 2020 Jul 31.

Non-Motor Symptoms in Cervical Dystonia: A Review

Affiliations

Non-Motor Symptoms in Cervical Dystonia: A Review

Somdattaa Ray et al. Ann Indian Acad Neurol. 2020 Jul-Aug.

Abstract

Dystonia is a movement disorder characterized by sustained or intermittent muscle contractions causing abnormal, often repetitive movements, postures, or both. Dystonic movements are typically patterned, associated with twisting of body parts, and may have tremulousness. Dystonia is usually initiated or worsened by voluntary action and associated with overflow muscle activation. Cervical dystonia (CD) is the most prevalent form of dystonia. CD is a condition characterized by cranial muscle overactivity leading to abnormal intermittent or continuous posturing of the head. Non-motor symptoms are comorbidity of dystonia, which significantly hampers the quality of life among these patients. The symptoms can be as a result of the dystonia itself. However, studies have highlighted the involvement of cortical-striatal-thalamocortical circuits in primary dystonia that could be the pathophysiological basis for the non-motor symptoms. The non-motor symptoms that are commonly associated with dystonia are anxiety, depression, restless leg syndrome, excessive daytime sleepiness, cognitive disturbances, and poor sleep. This review attempts to summarize the literature on non-motor symptoms in patients with CD.

Keywords: Anxiety; cervical dystonia; depression; non-motor; sleep.

PubMed Disclaimer

Conflict of interest statement

There are no conflicts of interest.

Figures

Figure 1
Figure 1
Methodology of selecting the articles

References

    1. Nutt JG, Muenter MD, Aronson A, Kurland LT, Melton LJ., 3rd Epidemiology of focal and generalized dystonia in Rochester, Minnesota. Mov Disord. 1988;3:188–94. - PubMed
    1. Camargo CHF, Teive HA, Becker N, Baran MH, Scola RH, Werneck LC. Cervical dystonia: Clinical and therapeutic features in 85 patients. Arq Neuropsiquiatr. 2008;66:15–21. - PubMed
    1. Fahn S. The varied clinical expressions of dystonia. Neurol Clin. 1984;2:541–54. - PubMed
    1. Klingelhoefer L, Martino D, Martinez-Martin P, Sauerbier A, Rizos A, Jost W, et al. Nonmotor symptoms and focal cervical dystonia: Observations from 102 patients. Basal Ganglia. 2014;4:117–20.
    1. Egger K, Mueller J, Schocke M, Brenneis C, Rinnerthaler M, Seppi K, et al. Voxel based morphometry reveals specific gray matter changes in primary dystonia. Mov Disord. 2007;22:1538–42. - PubMed