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. 2020 Jul-Dec;26(2):135-141.
doi: 10.4103/njs.NJS_68_19. Epub 2020 Jul 27.

The Effect of Single-Dose Bupivacaine on Postoperative Iliac Crest Graft Donor Site Pain

Olalere Omoyosola Gbolahan  1 , Babatunde Babasola Osinaike  2 , Adeola Olanike Olusanya  1 , Michael Oluyinka Okunola  3
Affiliations

The Effect of Single-Dose Bupivacaine on Postoperative Iliac Crest Graft Donor Site Pain

Olalere Omoyosola Gbolahan et al. Niger J Surg. 2020 Jul-Dec.

Abstract

Background: Postoperative donor site pain remains a major source of morbidity following iliac crest bone graft harvesting (ICBGH).

Aim: The aim of this study was to investigate the effect of single-dose infiltration of bupivacaine on donor site pain following ICBGH.

Subjects and methods: This study was a double-blind randomized controlled trial of 30 adult individuals that required an ICBG as part of the treatment for mandibular reconstruction. Individuals were divided into two groups, to receive a single-dose subcutaneous infiltration of either 0.25% bupivacaine or 0.9% normal saline at the iliac crest graft incision site following ICBGH. Length of incision at the ICBGH site, dimensions of harvested graft, time taken for the iliac crest harvest surgery, total daily dose of postoperative analgesics, pain from the ICBGH site as well as gait disturbance were recorded. Data were analyzed using SPSS version 17.0, and P < 0.05 was considered statistically significant.

Results: There was a progressive decrease in pain score from the 1st to the 4th postoperative day, with no significant difference between the two groups. There was no statistical difference between the two groups in terms of dynamic median pain score at the early postoperative period as well as at the 4th and 12th week postoperative period. The analgesic consumption between the two groups also did not show any significant difference.

Conclusion: Local injection of single dose of 0.25% bupivacaine did not offer additional benefit in the management of postoperative iliac crest donor site pain following ICBGH.

Keywords: Analgesic; bupivacaine; iliac crest bone graft harvesting; normal saline; pain.

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Conflict of interest statement

There are no conflicts of interest.

Figures

Figure 1
Figure 1
Postoperative median pain score (Numeric Rating Scale) in the first 4 days
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References

    1. Ahlmann E, Patzakis M, Roidis N, Shepherd L, Holtom P. Comparison of anterior and posterior iliac crest bone grafts in terms of harvest-site morbidity and functional outcomes. J Bone Joint Surg Am. 2002;84:716–20. - PubMed
    1. Cricchio G, Lundgren S. Donor site morbidity in two different approaches to anterior iliac crest bone harvesting. Clin Implant Dent Relat Res. 2003;5:161–9. - PubMed
    1. Nocini PF, Bedogni A, Valsecchi S, Trevisiol L, Ferrari F, Fior A, et al. Fractures of the iliac crest following anterior and posterior bone graft harvesting. Review of the literature and case presentation. Minerva Stomatol. 2003;52:441. - PubMed
    1. Barkhuysen R, Meijer GJ, Soehardi A, Merkx MA, Borstlap WA, Berge SJ, et al. The effect of a single dose of bupivacaine on donor site pain after anterior iliac crest bone harvesting. Int J Oral Maxillofac Surg. 2010;39:260–5. - PubMed
    1. Swan MC, Goodacre TE. Morbidity at the iliac crest donor site following bone grafting of the cleft alveolus. Br J Oral Maxillofac Surg. 2006;44:129–33. - PubMed