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Case Reports
. 2020 Oct 22;12(10):e11089.
doi: 10.7759/cureus.11089.

Tetanus After Trivial Trauma: A Case Series and Review of Pharamocotherapeutic Management

Affiliations
Case Reports

Tetanus After Trivial Trauma: A Case Series and Review of Pharamocotherapeutic Management

Nitin Gupta et al. Cureus. .

Abstract

Tetanus is a vaccine-preventable disease that is still endemic in developing countries. We discuss two cases of tetanus in unvaccinated individuals. The first case was a young goat herder who was initially started on benzodiazepine and muscle relaxants. Magnesium sulphate was added later on due to inadequate control after which the patient improved significantly. The second case was an old farmer who was started on magnesium sulphate along with benzodiazepine from the outset. His clinical recovery was faster compared to the first case. We report these cases to discuss the pharmacological options in the management of generalized tetanus with particular reference to magnesium sulphate.

Keywords: atracurium; clostridium tetani; diazepam; magnesium sulphate.

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Conflict of interest statement

The authors have declared that no competing interests exist.

References

    1. Tetanus: pathophysiology, management, and prophylaxis. Bleck TP. Dis Mon. 1991;37:545–603. - PubMed
    1. Clinical features and outcomes of tetanus: a retrospective study. Fan Z, Zhao Y, Wang S, Zhang F, Zhuang C. Infect Drug Resist. 2019;12:1289–1293. - PMC - PubMed
    1. Case fatality of adult tetanus in Africa: systematic review and meta-analysis. Woldeamanuel YW, Andemeskel AT, Kyei K, Woldeamanuel MW, Woldeamanuel W. J Neurol Sci. 2016;368:292–299. - PubMed
    1. Tetanus: a potential public health threat in times of disaster. Finkelstein P, Teisch L, Allen CJ, Ruiz G. Prehosp. Disaster Med. 2017;32:339–342. - PubMed
    1. Treatment of tetanus: an open study to compare the efficacy of procaine penicillin and metronidazole. Ahmadsyah I, Salim A. Br Med J Clin Res Ed. 1985;291:648–650. - PMC - PubMed

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