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Review
. 2021 Jan;12(1):8-12.
doi: 10.1111/1759-7714.13746. Epub 2020 Nov 22.

Diagnostic value of microRNAs for malignant pleural mesothelioma: A mini-review

Yan-Qiu Han  1 , Shang-Cheng Xu  2 , Wen-Qi Zheng  1 , Zhi-De Hu  1
Affiliations
Review

Diagnostic value of microRNAs for malignant pleural mesothelioma: A mini-review

Yan-Qiu Han et al. Thorac Cancer. 2021 Jan.

Abstract

Malignant pleural mesothelioma (MPM) is a type of cancer originating from the pleura with high aggressiveness and poor prognosis. A timely diagnosis is crucial to improve its prognosis. Laboratory biomarkers have significant advantages of reduced invasiveness, low cost, and are observer-independent, and therefore represent a promising diagnostic tool for MPM. MicroRNA is a family of non-coding RNA that regulates gene expression at the post-transcriptional level. Accumulated studies showed that microRNA, either in tissue, circulating, and body fluid, has potential diagnostic value for various disorders. Here, we reviewed the diagnostic value of microRNA for MPM.

Keywords: Diagnosis; malignant pleural mesothelioma; microRNA; review.

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Figure 1
Figure 1
Diagnostic microRNAs in tumor tissue, pleural effusion and circulation.
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