Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2021 Jan 4;13(1):a037788.
doi: 10.1101/cshperspect.a037788.

The Naming of Memory T-Cell Subsets

Stephen C Jameson  1
Affiliations
Review

The Naming of Memory T-Cell Subsets

Stephen C Jameson. Cold Spring Harb Perspect Biol. .

Abstract

With ever-improving methods of cell characterization, the field of immunology has enjoyed unprecedented opportunities to resolve distinctions between lymphocyte populations. However, this has led to a proliferation of "subset" designations that threatens to complicate and confuse clear identification of populations that share critical functional traits. This article discusses some of the challenges associated with a uniform approach to assigning subset designations to memory T-cell populations.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. Akondy RS, Fitch M, Edupuganti S, Yang S, Kissick HT, Li KW, Youngblood BA, Abdelsamed HA, McGuire DJ, Cohen KW, et al. 2017. Origin and differentiation of human memory CD8 T cells after vaccination. Nature 552: 362–367. 10.1038/nature24633 - DOI - PMC - PubMed
    1. Berg RE, Forman J. 2006. The role of CD8 T cells in innate immunity and in antigen non-specific protection. Curr Opin Immunol 18: 338–343. 10.1016/j.coi.2006.03.010 - DOI - PubMed
    1. Blank CU, Haining WN, Held W, Hogan PG, Kallies A, Lugli E, Lynn RC, Philip M, Rao A, Restifo NP, et al. 2019. Defining “cell exhaustion.” Nat Rev Immunol 19: 665–674. 10.1038/s41577-019-0221-9 - DOI - PMC - PubMed
    1. Böttcher JP, Beyer M, Meissner F, Abdullah Z, Sander J, Höchst B, Eickhoff S, Rieckmann JC, Russo C, Bauer T, et al. 2015. Functional classification of memory CD8+ T cells by CX3CR1 expression. Nat Commun 6: 8306 10.1038/ncomms9306 - DOI - PMC - PubMed
    1. Cheuk S, Wikén M, Blomqvist L, Nylén S, Talme T, Ståhle M, Eidsmo L. 2014. Epidermal Th22 and Tc17 cells form a localized disease memory in clinically healed psoriasis. J Immunol 192: 3111–3120. 10.4049/jimmunol.1302313 - DOI - PMC - PubMed

LinkOut - more resources