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Observational Study
. 2020 Dec;68(12):3012-3015.
doi: 10.4103/ijo.IJO_218_20.

Pupillodynamics and corneal spherical aberrations in a set of Indian cataract patients and its implications for aberrometric customisation of intraocular lenses

Mukesh J Paryani  1 , Varun Kharbanda  2 , Mathew Kurian Kummelil  3 , Kareeshma Wadia  4 , Ambarish B Darak  5
Affiliations
Observational Study

Pupillodynamics and corneal spherical aberrations in a set of Indian cataract patients and its implications for aberrometric customisation of intraocular lenses

Mukesh J Paryani et al. Indian J Ophthalmol. 2020 Dec.

Abstract

Purpose: Assessment of pupil diameter in various light conditions and the corresponding corneal spherical aberrations in a cohort of Indian eyes with bilateral senile cataracts and the possible use of this data in aberrometric customization of intraocular lenses (IOLs).

Methods: In this prospective observational study done at a tertiary eye care centre in India, the selected patients were subjected to measurement of their pupil diameters in scotopic, mesopic, and photopic conditions as well as the corresponding corneal spherical aberrations, using the Sirius Topographer (Costruzione Strumenti Oftalmici, Florence, Italy). Shapiro-Wilk test, Independent t-test, ANOVA with Bonferroni correction on post-hoc testing were used for statistical analysis.

Results: 104 eyes of 52 patients were enrolled for the study. The mean age was 53 ± 11.88 years. The mean scotopic, mesopic, and photopic pupil sizes were 4.37 mm (4.11-4.63 mm), 3.92 mm (3.71 mm-4.15 mm), and 3.37 mm (3.18-3.67 mm), respectively. There was a statistically significant difference (P = <0.001) in the mean corneal spherical aberration measured at the 6 mm zone (0.23 ± 0.02 microns) and at the 4 mm zone (0.06 ± 0.01 microns).

Conclusion: The mean corneal spherical aberration corresponding to the average mesopic pupil size of our patient population was substantially lower than that of the scotopic pupil size and also less than the amount corrected by most of the negative aspheric IOLs. This perhaps indicates the need for customising IOLs based on the spherical aberrations of cornea at the zone corresponding to the mesopic pupil diameter for optimal residual total postoperative spherical aberrations.

Keywords: Aspheric IOLs; corneal spherical aberration; pupillometry.

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Conflict of interest statement

None

Figures

Figure 1
Figure 1
Pupil diameter measurement by Sirius Topographer CSO
Figure 2
Figure 2
Shows Corneal Spherical aberrations (CSA) measured by Sirius topographer CSO. The pupil diameter at which CSA is measured can be selected from Bar on Y-axis
Figure 3
Figure 3
Shows measured OD and OS corneal spherical aberrations measured at 4 mm (CSA4) and 6 mm (CSA 6) zone
See this image and copyright information in PMC

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