Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2021 Mar 1;40(3):e117-e119.
doi: 10.1097/INF.0000000000002996.

Systemic Cat-Scratch Disease: a "Troublesome" Diagnosis

Affiliations
Case Reports

Systemic Cat-Scratch Disease: a "Troublesome" Diagnosis

Marco Sarno et al. Pediatr Infect Dis J. .

Abstract

Diagnosis of systemic cat scratch disease may be challenging. Here, we describe a case of an immunocompetent girl exhibiting fever and multifocal hepatosplenic abscesses. Diagnostic tests for Bartonella henselae infection (enzyme immunoassay and polymerase chain reaction) were found steadily negative and the diagnosis, suspected on the basis of the Margilet's criteria, was finally confirmed by indirect immunofluorescent antibodies.

PubMed Disclaimer

Conflict of interest statement

The authors have no conflicts of interest to disclose.

References

    1. Nawrocki CC, Max RJ, Marzec NS, et al. Atypical manifestations of cat-scratch disease, United States, 2005–2014. Emerg Infect Dis. 2020;26:1438–1446.
    1. Margileth AM. Recent advances in diagnosis and treatment of cat scratch disease. Curr Infect Dis Rep. 2000;2:141–146.
    1. Vermeulen MJ, Herremans M, Verbakel H, et al. Serological testing for Bartonella henselae infections in The Netherlands: clinical evaluation of immunofluorescence assay and ELISA. Clin Microbiol Infect. 2007;13:627–634.
    1. Jost M, Latz A, Ballhorn W, et al. Development of a specific and sensitive enzyme-linked immunosorbent assay as an in vitro diagnostic tool for detection of Bartonella henselae antibodies in human serum. J Clin Microbiol. 2018;56:e01329–18.
    1. Allizond V, Costa C, Sidoti F, et al. Serological and molecular detection of Bartonella henselae in specimens from patients with suspected cat scratch disease in Italy: a comparative study. PLoS One. 2019;14:e0211945.

Publication types

MeSH terms