Systemic Cat-Scratch Disease: a "Troublesome" Diagnosis
- PMID: 33230057
- DOI: 10.1097/INF.0000000000002996
Systemic Cat-Scratch Disease: a "Troublesome" Diagnosis
Abstract
Diagnosis of systemic cat scratch disease may be challenging. Here, we describe a case of an immunocompetent girl exhibiting fever and multifocal hepatosplenic abscesses. Diagnostic tests for Bartonella henselae infection (enzyme immunoassay and polymerase chain reaction) were found steadily negative and the diagnosis, suspected on the basis of the Margilet's criteria, was finally confirmed by indirect immunofluorescent antibodies.
Copyright © 2020 Wolters Kluwer Health, Inc. All rights reserved.
Conflict of interest statement
The authors have no conflicts of interest to disclose.
References
-
- Nawrocki CC, Max RJ, Marzec NS, et al. Atypical manifestations of cat-scratch disease, United States, 2005–2014. Emerg Infect Dis. 2020;26:1438–1446.
-
- Margileth AM. Recent advances in diagnosis and treatment of cat scratch disease. Curr Infect Dis Rep. 2000;2:141–146.
-
- Vermeulen MJ, Herremans M, Verbakel H, et al. Serological testing for Bartonella henselae infections in The Netherlands: clinical evaluation of immunofluorescence assay and ELISA. Clin Microbiol Infect. 2007;13:627–634.
-
- Jost M, Latz A, Ballhorn W, et al. Development of a specific and sensitive enzyme-linked immunosorbent assay as an in vitro diagnostic tool for detection of Bartonella henselae antibodies in human serum. J Clin Microbiol. 2018;56:e01329–18.
-
- Allizond V, Costa C, Sidoti F, et al. Serological and molecular detection of Bartonella henselae in specimens from patients with suspected cat scratch disease in Italy: a comparative study. PLoS One. 2019;14:e0211945.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical
Miscellaneous
