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. 2020 Nov 23;23(1):2.
doi: 10.1007/s11906-020-01119-0.

Electronic Cigarette Use and Blood Pressure Endpoints: a Systematic Review

Irene Martinez-Morata  1 , Tiffany R Sanchez  2 , Daichi Shimbo  3 , Ana Navas-Acien  4
Affiliations

Electronic Cigarette Use and Blood Pressure Endpoints: a Systematic Review

Irene Martinez-Morata et al. Curr Hypertens Rep. .

Abstract

Purpose of review: E-cigarettes (e-cigs) release toxic chemicals known to increase blood pressure (BP) levels. The effects of e-cigs on BP, however, remain unknown. Studying BP may help characterize potential cardiovascular risks of short- and long-term e-cig use. We summarized published studies on the association of e-cig use with BP endpoints.

Recent findings: Thirteen e-cig trials (12 cross-over designs) and 1 observational study evaluated systolic and diastolic blood pressure (SBP and DBP). All trials included at least one e-cig arm with nicotine, 6 a no-nicotine e-cig arm, and 3 a placebo arm. SBP/DBP increased in most nicotine e-cig arms, in some non-nicotine e-cig arms, and in none of the placebo arms. The observational study followed e-cig users and nonsmokers for 3.5 years with inconsistent findings. The use of e-cigs with and without nicotine may result in short-term elevations of both SBP and DBP. Prospective studies that investigate the long-term cardiovascular impact of e-cig use are needed.

Keywords: Blood pressure; Electronic-cigarettes; Hypertension; Nicotine.

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Conflict of interest statement

Conflict of Interest The authors declare that they have no conflict of interest.

Figures

Fig. 1
Fig. 1
PRISMA flow chart
Fig. 2
Fig. 2
Summary of the short-term SBP and DBP effects (between 0 and 120 min) of e-cigarette use with and without nicotine and placebo device in nonsmokers and smokers. Arrows indicate if blood pressure increased, decreased or remained the same. Light and dark red reflect nonsignificant and significant increases, light and dark blue reflect nonsignificant and significant decreases, respectively.
See this image and copyright information in PMC

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