Cancer-related cognitive impairment in patients with non-central nervous system malignancies: an overview for oncology providers from the MASCC Neurological Complications Study Group

Samantha J Mayo^{1

2}, Maryam Lustberg³, Haryana M Dhillon⁴, Zev M Nakamura⁵, Deborah H Allen⁶, Diane Von Ah⁷, Michelle C Janelsins^{8

9

10}, Alexandre Chan¹¹, Karin Olson¹², Chia Jie Tan¹³, Yi Long Toh¹³, Jeong Oh¹⁴, Lisa Grech^{15

16

17

18}, Yin Ting Cheung¹⁹, Ishwaria Mohan Subbiah¹⁴, Duska Petranovic²⁰, James D'Olimpio²¹, Margherita Gobbo^{22

23}, Susanne Koeppen²⁴, Charles L Loprinzi²⁵, Linda Pang²⁶, Shivani Shinde²⁷, Olanipekun Ntukidem²⁸, Katherine B Peters²⁹

Affiliations

¹ Lawrence S. Bloomberg Faculty of Nursing, University of Toronto, Toronto, Canada. samantha.mayo@utoronto.ca.
² Princess Margaret Cancer Centre, University Health Network, Toronto, Canada. samantha.mayo@utoronto.ca.
³ The Ohio State Comprehensive Cancer Center, Columbus, OH, USA.
⁴ University of Sydney, Sydney, Australia.
⁵ University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
⁶ Duke University Health System, Durham, NC, USA.
⁷ Indiana University School of Nursing, Indianapolis, IN, USA.
⁸ Department of Surgery, University of Rochester Medical Center, Rochester, NY, USA.
⁹ Department of Neuroscience, University of Rochester Medical Center, Rochester, NY, USA.
¹⁰ Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, NY, USA.
¹¹ University of California, Irvine, CA, USA.
¹² Faculty of Nursing, University of Alberta, Edmonton, Alberta, Canada.
¹³ The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
¹⁴ Peter MacCallum Cancer Centre, Parkville, Australia.
¹⁵ National University of Singapore, Singapore, Singapore.
¹⁶ Swinburne University, Hawthorn, Australia.
¹⁷ University of Melbourne, Parkville, Australia.
¹⁸ Monash University, Clayton, Australia.
¹⁹ School of Pharmacy, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, Hong Kong SAR.
²⁰ Clinical Hospital Center Rijeka, Faculty of Medicine, University of Rijeka, Rijeka, Croatia.
²¹ Monter Cancer Center, Northwell Cancer Institute, Lake Success, NY, USA.
²² Division of Oral Medicine and Pathology, Department of Medical, Surgical and Health Sciences, University of Trieste, Trieste, Italy.
²³ Unit of Oral and Maxillofacial Surgery, Ca Foncello Hospital, Treviso, Italy.
²⁴ LVR-Klinikum Essen, University of Duisburg-Essen, Essen, Germany.
²⁵ Mayo Clinic Rochester, Rochester, MN, USA.
²⁶ Kelsey-Seybold Clinic, Houston, TX, USA.
²⁷ Intermountain Health, Murray, UT, USA.
²⁸ St. Jude Children's Research Hospital, Memphis, TN, USA.
²⁹ The Preston Robert Tisch Brain Tumor Center, Duke University, Durham, NC, USA.

PMID: 33231809
DOI: 10.1007/s00520-020-05860-9

Review

Cancer-related cognitive impairment in patients with non-central nervous system malignancies: an overview for oncology providers from the MASCC Neurological Complications Study Group

Samantha J Mayo et al. Support Care Cancer. 2021 Jun.

. 2021 Jun;29(6):2821-2840.

doi: 10.1007/s00520-020-05860-9. Epub 2020 Nov 24.

Authors

Affiliations

¹ Lawrence S. Bloomberg Faculty of Nursing, University of Toronto, Toronto, Canada. samantha.mayo@utoronto.ca.
² Princess Margaret Cancer Centre, University Health Network, Toronto, Canada. samantha.mayo@utoronto.ca.
³ The Ohio State Comprehensive Cancer Center, Columbus, OH, USA.
⁴ University of Sydney, Sydney, Australia.
⁵ University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
⁶ Duke University Health System, Durham, NC, USA.
⁷ Indiana University School of Nursing, Indianapolis, IN, USA.
⁸ Department of Surgery, University of Rochester Medical Center, Rochester, NY, USA.
⁹ Department of Neuroscience, University of Rochester Medical Center, Rochester, NY, USA.
¹⁰ Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, NY, USA.
¹¹ University of California, Irvine, CA, USA.
¹² Faculty of Nursing, University of Alberta, Edmonton, Alberta, Canada.
¹³ The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
¹⁴ Peter MacCallum Cancer Centre, Parkville, Australia.
¹⁵ National University of Singapore, Singapore, Singapore.
¹⁶ Swinburne University, Hawthorn, Australia.
¹⁷ University of Melbourne, Parkville, Australia.
¹⁸ Monash University, Clayton, Australia.
¹⁹ School of Pharmacy, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, Hong Kong SAR.
²⁰ Clinical Hospital Center Rijeka, Faculty of Medicine, University of Rijeka, Rijeka, Croatia.
²¹ Monter Cancer Center, Northwell Cancer Institute, Lake Success, NY, USA.
²² Division of Oral Medicine and Pathology, Department of Medical, Surgical and Health Sciences, University of Trieste, Trieste, Italy.
²³ Unit of Oral and Maxillofacial Surgery, Ca Foncello Hospital, Treviso, Italy.
²⁴ LVR-Klinikum Essen, University of Duisburg-Essen, Essen, Germany.
²⁵ Mayo Clinic Rochester, Rochester, MN, USA.
²⁶ Kelsey-Seybold Clinic, Houston, TX, USA.
²⁷ Intermountain Health, Murray, UT, USA.
²⁸ St. Jude Children's Research Hospital, Memphis, TN, USA.
²⁹ The Preston Robert Tisch Brain Tumor Center, Duke University, Durham, NC, USA.

PMID: 33231809
DOI: 10.1007/s00520-020-05860-9

Abstract

Cancer-related cognitive impairment (CRCI) is commonly experienced by individuals with non-central nervous system cancers throughout the disease and treatment trajectory. CRCI can have a substantial impact on the functional ability and quality of life of patients and their families. To mitigate the impact, oncology providers must know how to identify, assess, and educate patients and caregivers. The objective of this review is to provide oncology clinicians with an overview of CRCI in the context of adults with non-central nervous system cancers, with a particular focus on current approaches in its identification, assessment, and management.

Keywords: CRCI; Cancer; Cancer-related cognitive impairment; Chemotherapy-related cognitive impairment; Cognition; Cognitive functioning.

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References

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Cancer-related cognitive impairment in patients with non-central nervous system malignancies: an overview for oncology providers from the MASCC Neurological Complications Study Group

Affiliations

Cancer-related cognitive impairment in patients with non-central nervous system malignancies: an overview for oncology providers from the MASCC Neurological Complications Study Group

Authors

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Abstract

References

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Medical