Escherichia coli Infection
- PMID: 33231968
- Bookshelf ID: NBK564298
Escherichia coli Infection
Excerpt
Escherichia coli (E. coli) is a gram-negative bacillus known to be a part of normal intestinal flora but can also be the cause of intestinal and extraintestinal illness in humans. There are hundreds of identified E. coli strains, resulting in a spectrum of disease from mild, self-limited gastroenteritis to renal failure and septic shock. Its virulence lends to E. coli’s ability to evade host defenses and develop resistance to common antibiotics. This review will divide E. coli infections into those causing intestinal illness and those causing extraintestinal illness.
Intestinal illnesses will be described by the causative E. coli subtypes, including enterotoxigenic Escherichia coli (ETEC), enterohemorrhagic Escherichia coli (EHEC), which is also known as Shiga toxin-producing Escherichia coli (STEC) and will be referred to as EHEC/STEC, enteroinvasive Escherichia coli (EIEC), enteropathogenic Escherichia coli (EPEC), and enteroaggregative Escherichia coli (EAEC). Extraintestinal illnesses will be described based on clinical disease.
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References
-
- Mylotte JM, Tayara A, Goodnough S. Epidemiology of bloodstream infection in nursing home residents: evaluation in a large cohort from multiple homes. Clin Infect Dis. 2002 Dec 15;35(12):1484-90. - PubMed
-
- McCue JD. Gram-negative bacillary bacteremia in the elderly: incidence, ecology, etiology, and mortality. J Am Geriatr Soc. 1987 Mar;35(3):213-8. - PubMed
-
- Jain S, Self WH, Wunderink RG, Fakhran S, Balk R, Bramley AM, Reed C, Grijalva CG, Anderson EJ, Courtney DM, Chappell JD, Qi C, Hart EM, Carroll F, Trabue C, Donnelly HK, Williams DJ, Zhu Y, Arnold SR, Ampofo K, Waterer GW, Levine M, Lindstrom S, Winchell JM, Katz JM, Erdman D, Schneider E, Hicks LA, McCullers JA, Pavia AT, Edwards KM, Finelli L, CDC EPIC Study Team Community-Acquired Pneumonia Requiring Hospitalization among U.S. Adults. N Engl J Med. 2015 Jul 30;373(5):415-27. - PMC - PubMed
-
- Sligl W, Taylor G, Brindley PG. Five years of nosocomial Gram-negative bacteremia in a general intensive care unit: epidemiology, antimicrobial susceptibility patterns, and outcomes. Int J Infect Dis. 2006 Jul;10(4):320-5. - PubMed
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