SPECT Imaging
- PMID: 33232084
- Bookshelf ID: NBK564426
SPECT Imaging
Excerpt
Single-photon emission computed tomography (SPECT) is a nuclear imaging modality frequently used in diagnostic medicine. At its most basic level, SPECT produces a three-dimensional image of the distribution of a radioactive tracer (sometimes called a probe) injected into the bloodstream and subsequently taken up by certain tissues.[1] This is accomplished using specialized nuclear medicine cameras. Thus, SPECT allows the clinician to assess the perfusion and functionality of specific tissues. The ability to assess tissue functionality and physiology sets SPECT imaging apart from purely anatomic imaging modalities such as computed tomography, magnetic resonance imaging, and roentgenography.
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- Israel O, Pellet O, Biassoni L, De Palma D, Estrada-Lobato E, Gnanasegaran G, Kuwert T, la Fougère C, Mariani G, Massalha S, Paez D, Giammarile F. Two decades of SPECT/CT - the coming of age of a technology: An updated review of literature evidence. Eur J Nucl Med Mol Imaging. 2019 Sep;46(10):1990-2012. - PMC - PubMed
-
- Hutton BF. The origins of SPECT and SPECT/CT. Eur J Nucl Med Mol Imaging. 2014 May;41 Suppl 1:S3-16. - PubMed
-
- Dougall NJ, Bruggink S, Ebmeier KP. Systematic review of the diagnostic accuracy of 99mTc-HMPAO-SPECT in dementia. Am J Geriatr Psychiatry. 2004 Nov-Dec;12(6):554-70. - PubMed
-
- Valotassiou V, Malamitsi J, Papatriantafyllou J, Dardiotis E, Tsougos I, Psimadas D, Alexiou S, Hadjigeorgiou G, Georgoulias P. SPECT and PET imaging in Alzheimer's disease. Ann Nucl Med. 2018 Nov;32(9):583-593. - PubMed
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