Response to comments on "A comparison of different physical stomach models and an analysis of shear stresses and strains in these system" by Wu and Chen (2020)

Abstract

Physical stomach (in-vitro) models have considerable potential for answering questions about the dissolution and delivery of tablets, as well as answering fundamental questions about the hydrodynamics of the stomach and ultimately investigating diseases of the human gastrointestinal system. Physical gastrointestinal models have been compared in terms of their advantages and disadvantages. The structures of the produced stomach parts have been compared among the in-vitro models. The possible materials to manufacture the stomach models have also been summarized. This letter to the editor responds to the correspondence by Wu and Chen (2020) about our paper, aiming to further check and describe the substance in our paper.

Keywords: Experimental stomach models; Hydrodynamics; Materials.