Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2020 Nov 20;17(22):8628.
doi: 10.3390/ijerph17228628.

Associations between Intensity, Frequency, Duration, and Volume of Physical Activity and the Risk of Stroke in Middle- and Older-Aged Chinese People: A Cross-Sectional Study

Donghui Yang  1 , Yuqian Bian  2 , Zixin Zeng  1 , Yiran Cui  1 , Yafeng Wang  1 , Chuanhua Yu  1
Affiliations

Associations between Intensity, Frequency, Duration, and Volume of Physical Activity and the Risk of Stroke in Middle- and Older-Aged Chinese People: A Cross-Sectional Study

Donghui Yang et al. Int J Environ Res Public Health. .

Abstract

Context: Persuasive evidence has shown the inverse associations between physical activity (PA) and the risk of stroke. However, few studies have investigated the associations between different dimensions (intensity, frequency, duration, volume) of PA and the risk of stroke.

Objective: To investigate the associations between different dimensions of PA and the risk of stroke in total participants and subgroups.

Method: This study included 6250 individuals aged 45 years old and above from the China Health and Retirement Longitudinal Study (CHARLS). PA was divided into vigorous PA (VPA), moderate PA (MPA), and light PA (LPA), and described in different dimensions (intensity, frequency, duration, volume). Stroke was defined on the basis of self-reported diagnosis and related treatments. Binary logistic regression models were established to assess the associations between different dimensions of PA and the risk of stroke in total participants and subgroups stratified by sex.

Results: Individuals taking VPA with a frequency of 3-5 d/w, duration of ≥240 min/d, volume of ≥300 min/w had lower risks of strokes in total participants (Odds ratio (OR) = 0.32, 95% confidence interval (CI): 0.13, 0.75; OR = 0.60, 95% CI: 0.38, 0.94; OR = 0.68, 95% CI: 0.46, 0.99, respectively). However, significant associations of VPA with the risk of stroke in men were only observed in the duration of ≥240 min/d and volume of ≥300 min/w (OR = 0.53, 95% CI: 0.30, 0.93; OR = 0.61, 95% CI: 0.38, 0.99, respectively) whereas no significance in women. Compared with individuals taking no MPA, inverse significant associations between the risk of stroke and any level of frequency, duration and volume in MPA were observed in total sample (OR ranging from 0.16-0.40, all p < 0.05), whereas significant associations between the risk of stroke and MPA were found in men except the duration of 10-29 min/d and volume of 150-299 min/w (OR ranging from 0.26-0.35, all p < 0.05), and in women except the frequency of 1-2 d/w and duration of ≥240 min/d (OR ranging from 0.14-0.49, all p < 0.05). No significant associations could be observed in total participants and subgroups between LPA and the risk of stroke.

Conclusion: This study revealed some significant associations between different dimensions of PA, especially MPA, and the risk of stroke. Furthermore, the difference of association was observed in the groups with different sex. Further prospective study is needed to determine deeper associations between PA and the risk of stroke.

Keywords: association; middle- and older-aged Chinese; physical activity (PA); stroke risk.

PubMed Disclaimer

Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Frequency of vigorous physical activity (VPA) (A), moderate physical activity (MPA) (B), and light physical activity (LPA) (C) in participants with and without stroke. The height of the column represents the proportion of individuals at this level of frequency in total participants with and without a stroke, respectively. Corresponding proportion is shown above the column.
Figure 2
Figure 2
Duration of VPA (A), MPA (B), and LPA (C) in participants with and without a stroke. The height of the column represents the proportion of individuals at this level of duration in total participants with and without a stroke, respectively. Corresponding proportion is shown above the column.
Figure 3
Figure 3
Volume of VPA (A), MPA (B), LPA (C) in participants with and without a stroke. The height of the column represents the proportion of individuals at this level of volume in participants with and without a stroke, respectively. Corresponding proportion is shown above the column.
See this image and copyright information in PMC

References

    1. Naghavi M., Abajobir A.A., Abbafati C., Abbas K.M., Abd-Allah F., Abera S.F., Aboyans V., Adetokunboh O., Afshin A., Agrawal A., et al. Global, regional, and national age-sex specific mortality for 264 causes of death, 1980–2016: A systematic analysis for the Global Burden of Disease Study 2016. Lancet. 2017;390:1151–1210. doi: 10.1016/S0140-6736(17)32152-9. - DOI - PMC - PubMed
    1. Avan A., Digaleh H., Di Napoli M., Stranges S., Behrouz R., Shojaeianbabaei G., Amiri A., Tabrizi R., Mokhber N., Spence J.D., et al. Socioeconomic status and stroke incidence, prevalence, mortality, and worldwide burden: An ecological analysis from the Global Burden of Disease Study 2017. BMC Med. 2019;17:191. doi: 10.1186/s12916-019-1397-3. - DOI - PMC - PubMed
    1. Global Burden of Disease Stroke Expert Group Global, Regional, and Country-Specific Lifetime Risks of Stroke, 1990 and 2016. N. Engl. J. Med. 2018;379:2429–2437. doi: 10.1056/NEJMoa1804492. - DOI - PMC - PubMed
    1. Wang Y.J., Li Z.X., Gu H.Q., Zhai Y., Jiang Y., Zhao X.Q., Wang Y.L., Yang X., Wang C.J., Meng X., et al. China Stroke Statistics 2019: A Report From the National Center for Healthcare Quality Management in Neurological Diseases, China National Clinical Research Center for Neurological Diseases, the Chinese Stroke Association, National Center for Chronic and Non-communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention and Institute for Global Neuroscience and Stroke Collaborations. Stroke Vasc. Neurol. 2020;5:211–239. doi: 10.1136/svn-2020-000457. - DOI - PMC - PubMed
    1. Wang W., Jiang B., Sun H., Ru X., Sun D., Wang L., Wang L., Jiang Y., Li Y., Wang Y., et al. Prevalence, Incidence, and Mortality of Stroke in China: Results from a Nationwide Population-Based Survey of 480 687 Adults. Circulation. 2017;135:759–771. doi: 10.1161/CIRCULATIONAHA.116.025250. - DOI - PubMed

Publication types