Realising the full potential of MR-PHeWAS in cancer
- PMID: 33235313
- PMCID: PMC7851387
- DOI: 10.1038/s41416-020-01165-0
Realising the full potential of MR-PHeWAS in cancer
Abstract
MR-PHeWAS is a powerful new design for discovering causal mechanisms between a disease and its many candidate risk factors in a hypothesis-free manner. This technique has great potential in the field of cancer research, provided that both powerful and principled statistical approaches are used.
Conflict of interest statement
The author declares no competing interests.
Comment on
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Searching for causal relationships of glioma: a phenome-wide Mendelian randomisation study.Br J Cancer. 2021 Jan;124(2):447-454. doi: 10.1038/s41416-020-01083-1. Epub 2020 Oct 6. Br J Cancer. 2021. PMID: 33020596 Free PMC article.
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