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. 2020 Sep 18;8(11):2286-2288.
doi: 10.1002/ccr3.3056. eCollection 2020 Nov.

Pure erythroid leukemia

Jason C Chen  1 , Winston Y Lee  2 , Jordan K Schaefer  1 , Dale L Bixby  1
Affiliations

Pure erythroid leukemia

Jason C Chen et al. Clin Case Rep. .

Abstract

The diagnosis of pure erythroid leukemia (PEL) can be challenging. Prompt identification of CD45+, CD34-, CD71+, CD117+, and E-cadherin+ erythroblasts is important. The differential diagnosis is broad and includes megaloblastic anemia.

Keywords: complex karyotype; erythroblast; erythroid leukemia; myeloid leukemia; tp53 mutation.

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Conflict of interest statement

None declared.

Figures

Figure 1
Figure 1
A Wright‐Giemsa stained bone marrow aspirate smear, original magnification ×1000
Figure 2
Figure 2
An H&E stained bone marrow core section, original magnification ×800
Figure 3
Figure 3
Immunohistochemical staining of a bone marrow core section for E‐cadherin, original magnification ×800
Figure 4
Figure 4
Metaphase karyotyping demonstrating a complex karyotype
See this image and copyright information in PMC

References

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