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[Preprint]. 2020 Nov 18:2020.11.14.20231811.
doi: 10.1101/2020.11.14.20231811.

Detection of the SARS-CoV-2 spike protein in saliva with Shrinky-Dink© electrodes

Julia A Zakashansky, Amanda H Imamura, Darwin F Salgado, Heather C Romero Mercieca, Raphael F L Aguas, Angelou M Lao, Joseph Pariser, Netzahualcóyotl Arroyo-Currás, Michelle Khine

Detection of the SARS-CoV-2 spike protein in saliva with Shrinky-Dink© electrodes

Julia A Zakashansky et al. medRxiv. .

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Abstract

Using the children's toy, Shrinky-Dink ©, we present an aptamer-based electrochemical (E-AB) assay that recognizes the spike protein of SARS-CoV-2 in saliva for viral infection detection. The low-cost electrodes are implementable at population scale and demonstrate detection down to 0.1 fg mL -1 of the S1 subunit of the spike protein.

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