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. 2020 Nov;31 Suppl 26(Suppl 26):69-71.
doi: 10.1111/pai.13338.

One step closer to influenza vaccine inclusiveness

Mayla Sgrulletti  1 , Giorgio Ottaviano  2 , Maria Sangerardi  3 , Loredana Chini  1 , Rosa Maria Dellepiane  4 , Baldassarre Martire  5 , Davide Montin  6 , Caterina Rizzo  7 , Viviana Moschese  1
Affiliations

One step closer to influenza vaccine inclusiveness

Mayla Sgrulletti et al. Pediatr Allergy Immunol. 2020 Nov.

Abstract

Flu virus infection is a common cause of acute respiratory illness, with the major incidence in pediatric age, high morbidity, and mortality. The flu vaccine is recommended for all people aged ≥6 months, unless specific contraindications are present. Younger and older age, pregnancy, chronic diseases like asthma, and immunodeficiency are risk factors for severe complications following flu infection. Thus, these categories represent the target for flu vaccine strategies in most countries. Inactivated influenza vaccine (IIV), recombinant influenza vaccine (RIV) or live-attenuated influenza virus (LAIV) are currently available, with specific precautions and contraindications. We aim to resume the current indications for vaccines in the vulnerable populations to support flu vaccination inclusiveness, in anticipation of a "universal vaccine" strategy.

Keywords: asthma; children; immunodeficiency; influenza vaccine; pregnancy; universal vaccine.

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Conflict of interest statement

All authors reported no conflicts of interest.

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