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. 2020 Nov:31 Suppl 26:26-28.
doi: 10.1111/pai.13362.

What impact of air pollution in pediatric respiratory allergic diseases

Giovanni Traina  1 , Andrea Barbalace  2 , Federica Betti  1 , Ezio Bolzacchini  3 , Maira Bonini  4 , Daniele Contini  5 , Giuseppe Felice  6 , Tiziana Foti  7 , Paride Mantecca  3
Affiliations

What impact of air pollution in pediatric respiratory allergic diseases

Giovanni Traina et al. Pediatr Allergy Immunol. 2020 Nov.

Abstract

Respiratory allergies are known to affect people all over the world. Environmental factors related to pollution play a significant etiopathogenic role in this regard. Polluting sources are industrial activities and urban traffic, capable of generating various types of pollutants that trigger inflammatory, direct, and indirect damage to tissues, promoting allergic symptoms, even serious ones, and interfering with the pharmacologic response. They are also able to modify pollen, promoting allergic sensitization. Pollution could have played a significant predisposing role in the ongoing morbidity and mortality of SARS-CoV-2.

Keywords: SARS-CoV-2; air pollution; asthma; oxidative stress; particulate matter; respiratory allergic disease.

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References

REFERENCES

    1. D'Amato G, Pawankar R, Vitale C, et al. Climate change and air pollution: effects on respiratory allergy. Allergy Asthma Immunol Res. 2016;8:391-395.
    1. Clifford RL, Jones MJ, Maclsaac JL. Inhalation of diesel exhaust and allergen alters human bronchial epithelium DNA methylation. J Allergy Clin Immunol. 2017;139:112-121.
    1. Riedl M, Diaz-Sanchez D. Biology of diesel exhaust effects on respiratory function. J Allergy Clin Immunol. 2005;115:221-228.
    1. Cilluffo G, Ferrante G, Fasola S, et al. Associations of greenness, greyness and air pollution exposure with children's health: a cross-sectional study in Southern Italy. Environ Health. 2018;17:86.
    1. Ruggieri S, Longo V, Perrino C, et al. Indoor air quality in schools of a highly polluted south Mediterranean area. Indoor Air. 2019;29:276-290.