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Observational Study
. 2021 Apr;18(2):164-175.
doi: 10.1111/iwj.13508. Epub 2020 Nov 25.

Groin wound infection after vascular exposure (GIVE) multicentre cohort study

Groin wound Infection after Vascular Exposure (GIVE) Study Group  1
Collaborators, Affiliations
Observational Study

Groin wound infection after vascular exposure (GIVE) multicentre cohort study

Groin wound Infection after Vascular Exposure (GIVE) Study Group. Int Wound J. 2021 Apr.

Abstract

Surgical site infections (SSIs) of groin wounds are a common and potentially preventable cause of morbidity, mortality, and healthcare costs in vascular surgery. Our aim was to define the contemporaneous rate of groin SSIs, determine clinical sequelae, and identify risk factors for SSI. An international multicentre prospective observational cohort study of consecutive patients undergoing groin incision for femoral vessel access in vascular surgery was undertaken over 3 months, follow-up was 90 days. The primary outcome was the incidence of groin wound SSI. 1337 groin incisions (1039 patients) from 37 centres were included. 115 groin incisions (8.6%) developed SSI, of which 62 (4.6%) were superficial. Patients who developed an SSI had a significantly longer length of hospital stay (6 versus 5 days, P = .005), a significantly higher rate of post-operative acute kidney injury (19.6% versus 11.7%, P = .018), with no significant difference in 90-day mortality. Female sex, Body mass index≥30 kg/m2 , ischaemic heart disease, aqueous betadine skin preparation, bypass/patch use (vein, xenograft, or prosthetic), and increased operative time were independent predictors of SSI. Groin infections, which are clinically apparent to the treating vascular unit, are frequent and their development carries significant clinical sequelae. Risk factors include modifiable and non-modifiable variables.

Keywords: vascular.

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Conflict of interest statement

The authors declare no potential conflict of interest.

Figures

FIGURE 1
FIGURE 1
Flow diagram of patient recruitment and outcomes
FIGURE 2
FIGURE 2
Funnel plot of SSI rates of each centre, with +/−2 and +/−3 SD lines
FIGURE 3
FIGURE 3
Funnel plot of deep and organ/space SSI rates of each centre, with +/−2 and +/− 3 SD lines
See this image and copyright information in PMC

References

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