COVID-19-Induced Acute Bilateral Optic Neuritis
- PMID: 33238757
- PMCID: PMC7705770
- DOI: 10.1177/2324709620976018
COVID-19-Induced Acute Bilateral Optic Neuritis
Abstract
A 44-year-old male patient with no past medical history presented 2 weeks after seropositive coronavirus disease 2019 (COVID-19) infection with vision problems suggestive of optic neuritis. Radiological testing showed findings suspicious for acute bilateral optic neuritis. The patient had also anti-MOG antibodies. Whether this was an optic neuritis due to COVID-19, MOG antibody disease, or an activation of MOG antibody disease by COVID-19 is discussed in this case.
Keywords: COVID-19; bilateral optic neuritis.
Conflict of interest statement
Figures



Similar articles
-
Myelin oligodendrocyte glycoprotein antibody-associated optic neuritis in a COVID-19 patient: A case report.Medicine (Baltimore). 2021 May 14;100(19):e25865. doi: 10.1097/MD.0000000000025865. Medicine (Baltimore). 2021. PMID: 34106635 Free PMC article.
-
Myelin oligodendrocyte glycoprotein antibody-associated optic neuritis in a post-COVID-19 infection patient.Immun Inflamm Dis. 2023 Oct;11(10):e1051. doi: 10.1002/iid3.1051. Immun Inflamm Dis. 2023. PMID: 37904693 Free PMC article.
-
Prevalence of serum MOG antibody and AQP4 antibody in optic neuritis after SARS-CoV-2 infection.Front Immunol. 2023 Nov 20;14:1296518. doi: 10.3389/fimmu.2023.1296518. eCollection 2023. Front Immunol. 2023. PMID: 38054007 Free PMC article.
-
SARS-CoV-2-related Myelin Oligodendrocyte Glycoprotein Antibody-associated Disease: A Case Report and Literature Review.Intern Med. 2022 Apr 15;61(8):1253-1258. doi: 10.2169/internalmedicine.8709-21. Epub 2022 Feb 8. Intern Med. 2022. PMID: 35135920 Free PMC article. Review.
-
Atypical myelin oligodendrocyte glycoprotein antibody-associated optic neuritis and acute demyelinating polyneuropathy after SARS-CoV-2 infection: Case report and literature review.J Neuroimmunol. 2023 Feb 15;375:578011. doi: 10.1016/j.jneuroim.2022.578011. Epub 2022 Dec 23. J Neuroimmunol. 2023. PMID: 36621074 Free PMC article. Review.
Cited by
-
Fifteen acute retrobulbar optic neuritis associated with COVID-19: A case report and review of literature.World J Clin Cases. 2024 Jul 26;12(21):4827-4835. doi: 10.12998/wjcc.v12.i21.4827. World J Clin Cases. 2024. PMID: 39070831 Free PMC article.
-
A review of neuro-ophthalmic sequelae following COVID-19 infection and vaccination.Front Cell Infect Microbiol. 2024 Jan 17;14:1345683. doi: 10.3389/fcimb.2024.1345683. eCollection 2024. Front Cell Infect Microbiol. 2024. PMID: 38299114 Free PMC article. Review.
-
COVID-19-associated optic neuritis - A case series and review of literature.Indian J Ophthalmol. 2022 Jan;70(1):310-316. doi: 10.4103/ijo.IJO_2235_21. Indian J Ophthalmol. 2022. PMID: 34937266 Free PMC article. Review.
-
Manifestations of COVID-19 in the posterior eye segment - Up-to-date.Oman J Ophthalmol. 2024 Jun 27;17(2):166-172. doi: 10.4103/ojo.ojo_212_22. eCollection 2024 May-Aug. Oman J Ophthalmol. 2024. PMID: 39132129 Free PMC article. Review.
-
Anti-myelin Oligodendrocyte Glycoprotein Antibody-positive Myelitis after Coronavirus Disease 2019.Intern Med. 2023 May 15;62(10):1531-1535. doi: 10.2169/internalmedicine.0394-22. Epub 2023 Mar 1. Intern Med. 2023. PMID: 36858516 Free PMC article.
References
-
- Balcer LJ. Optic neuritis. N Engl J Med. 2006;354:1273-1280. - PubMed
-
- Roed H, Frederiksen J, Langkilde A, Sørensen TL, Lauritzen M, Sellebjerg F. Systemic T-cell activation in acute clinically isolated optic neuritis. J Neuroimmunol. 2005;162:165-172. - PubMed
-
- Söderström M, Link H, Xu Z, Fredriksson S. Optic neuritis and multiple sclerosis: anti-MBP and anti-MBP peptide antibody-secreting cells are accumulated in CSF. Neurology. 1993;43:1215-1222. - PubMed
-
- Jacobs LD, Kaba SE, Miller CM, Priore RL, Brownscheidle CM. Correlation of clinical, magnetic resonance imaging, and cerebrospinal fluid findings in optic neuritis. Ann Neurol. 1997;41:392-398. - PubMed
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical
Miscellaneous