Mineralocorticoid Receptor Antagonists for Diabetic Kidney Disease
- PMID: 33239412
- PMCID: PMC7769027
- DOI: 10.2215/CJN.16201020
Mineralocorticoid Receptor Antagonists for Diabetic Kidney Disease
Keywords: aldosterone; chronic kidney disease; diabetes; microalbuminuria; mineralocorticoid receptor antagonists.
Comment on
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Esaxerenone (CS-3150) in Patients with Type 2 Diabetes and Microalbuminuria (ESAX-DN): Phase 3 Randomized Controlled Clinical Trial.Clin J Am Soc Nephrol. 2020 Dec 7;15(12):1715-1727. doi: 10.2215/CJN.06870520. Epub 2020 Nov 25. Clin J Am Soc Nephrol. 2020. PMID: 33239409 Free PMC article. Clinical Trial.
References
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- Barrera-Chimal J, Girerd S, Jaisser F: Mineralocorticoid receptor antagonists and kidney diseases: Pathophysiological basis. Kidney Int 96: 302–319, 2019. - PubMed
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- Hou J, Xiong W, Cao L, Wen X, Li A: Spironolactone add-on for preventing or slowing the progression of diabetic nephropathy: A meta-analysis. Clin Ther 37: 2086–2103.e10, 2015. - PubMed
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- Kolkhof P, Nowack C, Eitner F: Nonsteroidal antagonists of the mineralocorticoid receptor. Curr Opin Nephrol Hypertens 24: 417–424, 2015. - PubMed
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