Field Evaluation of Cholkit Rapid Diagnostic Test for Vibrio Cholerae O1 During a Cholera Outbreak in Malawi, 2018
- PMID: 33241067
- PMCID: PMC7676503
- DOI: 10.1093/ofid/ofaa493
Field Evaluation of Cholkit Rapid Diagnostic Test for Vibrio Cholerae O1 During a Cholera Outbreak in Malawi, 2018
Abstract
Rapid diagnostic tests (RDTs) for cholera are an important emerging tool for surveillance, yet the currently available tests have several limitations. We assess the performance of a new RDT, Cholkit, during a cholera outbreak in Malawi compared with culture and find a sensitivity of 93.0% (95% CI, 83.0%-98.1%) and a specificity of 95.7% (95% CI, 78.1%-100.0%).
Keywords: cholera; malawi; rapid test; vibrio cholerae.
© The Author(s) 2020. Published by Oxford University Press on behalf of Infectious Diseases Society of America.
References
-
- Ramamurthy T, Yamasaki S, Takeda Y, Nair GB. Vibrio cholerae O139 Bengal: odyssey of a fortuitous variant. Microbes Infect 2003; 5:329–44. - PubMed
-
- The Global Task Force on Cholera Control. Interim technical note the use of cholera rapid diagnostic tests 2016. Available at: http://www.who.int/cholera/task_force/Interim-guidance-cholera-RDT.pdf?ua=1. Accessed 30 October 2020.
