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Comment
. 2020 Nov 26;136(22):2489-2490.
doi: 10.1182/blood.2020008768.

Catch those antibodies before they fall

Beth H Shaz  1 , Claudia S Cohn  2
Affiliations
Comment

Catch those antibodies before they fall

Beth H Shaz et al. Blood. .

Abstract

In this issue of Blood, Perreault et al showed decreasing total antibody levels over time in 15 repeat COVID-19 convalescent plasma (CCP) donors with at least 4 donations. The decrease was greatest between the final 2 time points reported, from days 70 to 84 to days 85 to 114, after disease onset. This decrease was time dependent and independent of donation number.

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Conflict of interest statement

Conflict-of-interest disclosure: The authors declare no competing financial interests.

Conflict-of-interest disclosure: The authors declare no competing financial interests.

Figures

None
Collecting and transfusing high-titer CCP units early in hospitalization improves outcome. Studies have demonstrated that antibody levels are highest when donors are first eligible to donate. The high-titer CCP units when given soon after diagnosis or hospitalization improve patient outcomes.
See this image and copyright information in PMC

Comment on

References

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