Spending the Best but Banking the Rest
- PMID: 33242415
- DOI: 10.1016/j.cell.2020.11.006
Spending the Best but Banking the Rest
Abstract
All vaccines rely on the ability of B cells to remember pathogen infections and respond more vigorously upon reinfection. In this issue of Cell, Viant et al. address the real-world issue of protection against rapidly emerging pathogen variants and describe how memory B cells may anticipate infections by such variants.
Published by Elsevier Inc.
Comment on
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Antibody Affinity Shapes the Choice between Memory and Germinal Center B Cell Fates.Cell. 2020 Nov 25;183(5):1298-1311.e11. doi: 10.1016/j.cell.2020.09.063. Epub 2020 Oct 29. Cell. 2020. PMID: 33125897 Free PMC article.
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