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Comment
. 2020 Nov 25;108(4):583-585.
doi: 10.1016/j.neuron.2020.11.003.

What Does the APP Family Do in the Brain?

Ottavio Arancio  1
Affiliations
Comment

What Does the APP Family Do in the Brain?

Ottavio Arancio. Neuron. .

Abstract

Amyloid-β precursor protein (APP) is overshadowed by its degradation product, the Alzheimer protein Aβ. Lee et al. now find a role for the APP family in neuronal excitability, synaptic plasticity, and memory in adulthood, despite the lack of requirement for neuronal survival.

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Conflict of interest statement

Declaration of Interests The author declares that he is a founding member of Neurokine Therapeutics, LLC. He is also a consultant for Aribio Co., Ltd.

Comment on

References

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