Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2020 Sep 17;65(10):597-601.
doi: 10.18821/0869-2084-2020-65-10-597-601.

Chronic hyponatremia in the elderly: association with geriatric syndromes (review of literature)

S V Bulgakova  1 , E V Treneva  1 , N O Zakharova  1 , A V Nikolaeva  1 , E A Ovchinnikova  1
Affiliations
Review

Chronic hyponatremia in the elderly: association with geriatric syndromes (review of literature)

S V Bulgakova et al. Klin Lab Diagn. .

Abstract

Hyponatremia is more common in the elderly. A number of studies suggest that even mild chronic hyponatremia is a serious danger, increasing the risks of developing geriatric syndromes, falls, low bone density, fractures, cognitive impairment, and death of all causes. Although the mechanism for the development of such complications is currently not completely clear. Questions remain about the need and methods for correcting this condition, although there is some evidence that the correction of hyponatremia improves cognitive functions, postural balance, minimizing the risk of falls and fractures. These issues are addressed in this review of the literature.

Keywords: advanced age; bone mineral density; cognitive functions; falls; fractures; hyponatremia; osteoporosis; review; senile age.

PubMed Disclaimer

Conflict of interest statement

The authors declare no conflict of interest.

References

    1. Burst V. Etiology and Epidemiology of Hyponatremia. Front Horm. Res. 2019; 52: 24-35.
    1. Upadhyay A., Jaber B.L., Madias N.E. Incidence and prevalence of hyponatremia. Am. J. Med. 2006; 119: 30-5.
    1. Ayus J.C., Negri A.L., Kalantar-Zadeh K., Moritz M.L. Is chronic hyponatremia a novel risk factor for hip fracture in the elderly? Nephrol. Dial. Transplant. 2012; 27: 3725-31.
    1. Miller M. Hyponatremia and arginine vasopressin dysregulation: mechanisms, clinical consequences, and management. J. Am. Geriatr. Soc. 2006; 54: 345-53.
    1. Martin J., Burnier M., Lu H. Approach to the syndrome of inappropriate antidiuretic hormone secretion (SIADH). Rev. Med. Suisse. 2018; 14(628): 2116-20.

LinkOut - more resources