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Review
. 2020 Dec 23;27(8):taaa219.
doi: 10.1093/jtm/taaa219.

GeoSentinel: past, present and future†

Davidson H Hamer  1   2   3 , Aisha Rizwan  4 , David O Freedman  5 , Phyllis Kozarsky  6 , Michael Libman  7
Affiliations
Review

GeoSentinel: past, present and future†

Davidson H Hamer et al. J Travel Med. .

Abstract

Rationale for review: In response to increased concerns about emerging infectious diseases, GeoSentinel, the Global Surveillance Network of the International Society of Travel Medicine in partnership with the US Centers for Disease Control and Prevention (CDC), was established in 1995 in order to serve as a global provider-based emerging infections sentinel network, conduct surveillance for travel-related infections and communicate and assist global public health responses. This review summarizes the history, past achievements and future directions of the GeoSentinel Network.

Key findings: Funded by the US CDC in 1996, GeoSentinel has grown from a group of eight US-based travel and tropical medicine centers to a global network, which currently consists of 68 sites in 28 countries. GeoSentinel has provided important contributions that have enhanced the ability to use destination-specific differences to guide diagnosis and treatment of returning travelers, migrants and refugees. During the last two decades, GeoSentinel has identified a number of sentinel infectious disease events including previously unrecognized outbreaks and occurrence of diseases in locations thought not to harbor certain infectious agents. GeoSentinel has also provided useful insight into illnesses affecting different traveling populations such as migrants, business travelers and students, while characterizing in greater detail the epidemiology of infectious diseases such as typhoid fever, leishmaniasis and Zika virus disease.

Conclusions: Surveillance of travel- and migration-related infectious diseases has been the main focus of GeoSentinel for the last 25 years. However, GeoSentinel is now evolving into a network that will conduct both research and surveillance. The large number of participating sites and excellent geographic coverage for identification of both common and illnesses in individuals who have traversed international borders uniquely position GeoSentinel to make important contributions of travel-related infectious diseases in the years to come.

Keywords: COVID-19; Sentinel event; Zika; antimicrobial resistance; emerging infectious diseases; surveillance; travel medicine.

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Figures

Figure 1
Figure 1
Flow of GeoSentinel surveillance data
See this image and copyright information in PMC

References

    1. Morens DM, Folkers GK, Fauci AS. The challenge of emerging and re-emerging infectious diseases. Nature 2004; 430:242–9. doi: 10.1038/nature02759. - DOI - PMC - PubMed
    1. Morens DM, Folkers GK, Fauci AS. Emerging infections: a perpetual challenge. Lancet Infect Dis 2008; 8:710–9. doi: 10.1016/S1473-3099(08)70256-1. - DOI - PMC - PubMed
    1. Glaesser D, Kester J, Paulose H, Alizadeh A, Valentin B. Global travel patterns: an overview. J Travel Med 2017; 24:1–5. doi: 10.1093/jtm/tax007. - DOI - PubMed
    1. Chen LH, Leder K, Barbre KA et al. Business travel-associated illness: a GeoSentinel analysis. J Travel Med 2018; 25. doi: 10.1093/jtm/tax097. - DOI - PMC - PubMed
    1. Hagmann SHF, Han PV, Stauffer WM et al. Travel-associated disease among US residents visiting US GeoSentinel clinics after return from international travel. Fam Pract 2014; 31:678–87. doi: 10.1093/fampra/cmu063. - DOI - PMC - PubMed

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