Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 1987 Jul;16(3):444-8.

Biochemical modulation of fluorouracil therapy in advanced colorectal cancer

J Mackintosh  1 , M H Tattersall
Affiliations
  • PMID: 3324921
Review

Biochemical modulation of fluorouracil therapy in advanced colorectal cancer

J Mackintosh et al. Ann Acad Med Singap. 1987 Jul.

Abstract

Fluorouracil has been the mainstay of chemotherapy in colorectal cancer for many years. We report our experience using fluorouracil in combination with other drugs which may modulate the spectrum of activity. Patients have been treated with allopurinol and fluorouracil and with two schedules of methotrexate and fluorouracil. We discuss other possible approaches to modulate fluorouracil action.

PubMed Disclaimer

MeSH terms