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Review
. 2021 Mar;23(3):467-474.
doi: 10.1111/jch.14111. Epub 2020 Nov 29.

Isolated systolic hypertension in Asia

Tsung-Ying Tsai  1 , Hao-Min Cheng  1   2   3   4 , Shao-Yuan Chuang  5 , Yook-Chin Chia  6   7 , Arieska Ann Soenarta  8 , Huynh Van Minh  9 , Saulat Siddique  10 , Yuda Turana  11 , Jam Chin Tay  12 , Kazuomi Kario  13 , Chen-Huan Chen  1   2   3   4
Affiliations
Review

Isolated systolic hypertension in Asia

Tsung-Ying Tsai et al. J Clin Hypertens (Greenwich). 2021 Mar.

Abstract

Isolated systolic hypertension (ISH) is the most common type of essential hypertension in the elderly and young adults. With rapid industrialization and population aging, the prevalence of ISH in Asia will rise substantially. Asian populations have distinct epidemiological features, risk factors and are especially vulnerable to ISH. There is a pressing need for Asian countries to formulate their unique strategies for control of ISH. In this review, we focus on the (1) epidemiology and pathophysiology, (2) risk factors and impact on outcomes, and (3) treatment goal and strategy for ISH in Asia.

Keywords: Asia; hypertension; isolated systolic hypertension.

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Conflict of interest statement

YC Chia has received speakers honorarium and sponsorship to attend conferences and CME seminars from Abbott, Bayer, Boehringer Ingelheim, GlaxoSmithKline, Menarini, Merck Sharp & Dohme, Novartis, Omron, Pfizer, Sanofi Xepa‐Soul and a research grant from Pfizer. S Siddique has received honoraria from Bayer, Novartis, Pfizer, ICI, and Servier; and travel, accommodation, and conference registration support from Hilton Pharma, Atco Pharmaceutical, Highnoon Laboratories, Horizon Pharma and ICI. K Kario received research grant from A &D Co., Omron Healthcare Co., Fukuda Denshi Co., MSD KK, Astellas Pharma Inc, Eisai Co., Otsuka Pharmaceutical Co., Otsuka Holdings Co., Sanofi KK, Shionogi & Co., Sanwa Kagaku Kenkyusho Co., Daiichi Sankyo Co., Taisho Pharmaceutical Co., Ltd, Sumitomo Dainippon Pharma Co., Takeda Pharmaceutical Co., Mitsubishi Tanabe Pharma Co., Teijin Pharma, Boehringer Ingelheim Japan Inc, Pfizer Japan Inc, Bristol‐Myers Squibb KK, Mylan Co., Mochida Pharmaceutical Co., Roche Diagnostics KK and honoraria from Idorsia Pharmaceuticals Japan, Omron Healthcare Co., Daiichi Sankyo Company, Limited, Takeda Pharmaceutical Co., Terumo Corporation, Mylan EPD. CH Chen reports personal fees from Novartis, Sanofi, Daiichi Sankyo, SERVIER, and Boehringer Ingelheim Pharmaceuticals, Inc All other authors report no potential conflicts of interest in relation to this article.

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