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Review
. 2020 Oct;34(10):958-960.
doi: 10.13201/j.issn.2096-7993.2020.10.023.

[Progress in obstructive sleep apnea and atherosclerosis]

[Article in Chinese]
Haili Sun, Yanwen Qin, Yongxiang Wei
Review

[Progress in obstructive sleep apnea and atherosclerosis]

[Article in Chinese]
Haili Sun et al. Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2020 Oct.

Abstract

Obstructive sleep apnea（OSA） is a common sleep-disordered disease which is characterized by repetitive narrowing or occlusion of the pharynx causing intermittent hypoxia, repetitive arousals, sleep deprivation, and excessive daytime sleepiness. OSA can contribute to atherosclerosis through direct and indirect mechanisms. Animal and clinical studies have shown a close relationship between OSA and atherosclerosis and its risk factors. However, current studies showed inconsistent results. In the future, further research both basic and clinical studies need to be fulfilled. Future studies are needed to investigate underlying mechanisms between OSA and atherosclerosis.

Keywords: atherosclerosis; endothelial function; intermittent hypoxia; sleep apnea, obstructive.

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Conflict of interest statement

The authors of this article and the planning committee members and staff have no relevant financial relationships with commercial interests to disclose.

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