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. 2020 Dec;34(12):1108-1111.
doi: 10.13201/j.issn.2096-7993.2020.12.012.

[Comparison of acellular dermal allograft and tragus cartilage perichondrium in type Ⅰ tympanoplasty under otoendoscopy]

[Article in Chinese]
Haojie Wen  1 , Jinyong Tang  1 , Minghua Hou  1 , Yi Cui  1
Affiliations

[Comparison of acellular dermal allograft and tragus cartilage perichondrium in type Ⅰ tympanoplasty under otoendoscopy]

[Article in Chinese]
Haojie Wen et al. Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2020 Dec.

Abstract
in English, Chinese

Objective:To compare the therapeutic effect of otoendoscopic tympanoplasty with acellular dermal allograft（AlloDerm） and tragus cartilage perichondrium. Method:121 patients who underwent type Ⅰ tympanoplasty under otoscope were retrospectively analyzed. According to the grafts used, they were divided into two groups: AlloDerm group （56 cases） and tragus cartilage perichondrium group （65 cases）. The operative time, postoperative tympanic membrane healing rate, and hearing recovery were compared between two groups. The follow-up time was twelve months. Result:The operative time in the AlloDerm group were lower than those in the tragus cartilage perichondrium group（P<0.05）. The successful closure rates between the acellular dermal allograft group and tragus cartilage perichondrium group at 1-month follow-up were 92.86% and 92.31% respectively, while the closure rates between two groups at 6-month follow-up were drop to 91.07% and 90.77% respectively, the closure rates between two groups at 12-month follow-up were also 91.07% and 90.77% respectively,the was no statistically difference between two groups（P>0.05）. The difference in pre-and post-operative air bone gap（ABG） values between two groups was no statistically significant（P>0.05）. Conclusion:Both the AlloDerm and the tragus cartilage perichondrium tympanoplasty can achieve satisfactory healing rate of the tympanic membrane and audiologic improvement. However, AlloDerm has a short operation time, no need to obtain materials and less trauma, and is worth of promotion and application.

目的：比较耳内镜下脱细胞异体真皮与耳屏软骨-软骨膜行Ⅰ型鼓室成形术的疗效。 方法：回顾性分析行耳内镜下Ⅰ型鼓室成形术的患者共121例（121耳），按采用的修补材料分为脱细胞异体真皮组（异体真皮组）56例（56耳）和耳屏软骨-软骨膜复合体组（软骨组）65例（65耳）。比较2组手术时间、术后鼓膜愈合率、听力恢复情况。随访12个月。 结果：异体真皮组与软骨组手术时间分别为（59.29±6.48） min和（70.78±7.31） min，2组手术时间比较差异有统计学意义（P<0.05）。术后1个月鼓膜愈合率分别为92.86%、92.31%，术后6个月分别为91.07%、90.77%，术后12个月分别为91.07%、90.77%，2组术后1、6、12个月鼓膜愈合率比较差异均无统计学意义（P>0.05）。2组术后12个月听力恢复情况比较差异无统计学意义（P>0.05）。 结论：耳内镜下采用脱细胞异体真皮及耳屏软骨-软骨膜行Ⅰ型鼓室成形术疗效确切，能提高鼓膜愈合率及改善患者听力效果。前者手术时间短，无需取材创伤小，值得推广应用。.

Keywords: acellular dermal allograft; otoendoscopy; tragus cartilage perichondrium; treatment effectiveness; tympanoplasty.

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Conflict of interest statement

The authors of this article and the planning committee members and staff have no relevant financial relationships with commercial interests to disclose.

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