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Clinical Trial
. 1987 Nov;23(11):1125-7.

Topical application of human fibroblast interferon (IFN) in cutaneous leishmaniasis

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  • PMID: 3325468
Clinical Trial

Topical application of human fibroblast interferon (IFN) in cutaneous leishmaniasis

H Trau et al. Isr J Med Sci. 1987 Nov.

Abstract

Fifteen patients with single or multiple lesions of cutaneous leishmaniasis were randomly assigned to apply either IFN-beta-containing cream or a placebo cream base. Despite 8 weeks of therapy no significant improvement of the lesions was achieved. Although topical IFN-beta was not effective in this study, several laboratory studies suggest that IFN, particularly IFN-gamma, may be of therapeutic value in cutaneous leishmaniasis.

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