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Review
. 2021 Feb;17(2):81-82.
doi: 10.1038/s41581-020-00381-4.

The COVID-19 pandemic: consequences for nephrology

Annette Bruchfeld  1   2
Affiliations
Review

The COVID-19 pandemic: consequences for nephrology

Annette Bruchfeld. Nat Rev Nephrol. 2021 Feb.

Abstract

The consequences of the COVID-19 pandemic have been devastating; however, evidence suggests that patients with, or at risk of, kidney disease are disproportionally affected. Patients on dialysis and kidney transplant recipients are at higher risk of adverse outcomes from COVID-19, whereas, conversely, patients with severe COVID-19 are at increased risk of acute kidney injury, with short-term and possibly long-term consequences for nephrological care.

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Conflict of interest statement

A.B. has received grants and personal fees from AstraZeneca and personal fees from ChemoCentryx, Merck/MSD, Vifor and Abbvie, outside the submitted work.

Figures

Fig. 1
Fig. 1. The impact of COVID-19 on the kidneys.
a | Patients on in-centre dialysis and kidney transplant recipients are at increased risk of community exposure to SARS-CoV-2 infection and COVID-19-associated mortality. b | Acute kidney injury (AKI) is also an important complication of severe COVID-19, likely as a consequence of multifactorial processes, and is associated with an increased risk of mortality. ICU, intensive care unit.
See this image and copyright information in PMC

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References

    1. Cheng Y, et al. Kidney disease is associated with in-hospital death of patients with COVID-19. Kidney Int. 2020;97:829–838. doi: 10.1016/j.kint.2020.03.005. - DOI - PMC - PubMed
    1. Petrilli CM, et al. Factors associated with hospital admission and critical illness among 5279 people with coronavirus disease 2019 in New York City: prospective cohort study. BMJ. 2020;369:m1966. doi: 10.1136/bmj.m1966. - DOI - PMC - PubMed
    1. Williamson EJ, et al. Factors associated with COVID-19-related death using OpenSAFELY. Nature. 2020;584:430–436. doi: 10.1038/s41586-020-2521-4. - DOI - PMC - PubMed
    1. Anand S, et al. Prevalence of SARS-CoV-2 antibodies in a large nationwide sample of patients on dialysis in the USA: a cross-sectional study. Lancet. 2020;396:1335–1344. doi: 10.1016/S0140-6736(20)32009-2. - DOI - PMC - PubMed
    1. Jager KJ, et al. Results from the ERA-EDTA Registry indicate a high mortality due to COVID-19 in dialysis patients and kidney transplant recipients across Europe. Kidney Int. 2020 doi: 10.1016/j.kint.2020.09.006. - DOI - PMC - PubMed

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