[Effect of antibiotics at subinhibitory concentrations on alpha-hemolysin production in uropathogenic Escherichia coli]

Abstract

The action of subinhibitory concentrations of seven antibiotics (Mezlocillin, Streptomycin, Tobramycin, Chloramphenicol, Tetracycline, Nalidixic acid and Pefloxacin) on the ability to produce alpha-hemolysin are studied on six strains of uropathogenic E. coli. At CMI 2 most of the antibiotics have an inhibitory action. At lower concentrations Pefloxacin, Tetracycline, Streptomycin (in the decrease order) have still an action. Some variations in determinations are observed in function of the choice of the antibiotics and also in function of the stains of E. coli studied.