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Practice Guideline
. 2021 Jan;28(1):26-54.
doi: 10.1002/jhbp.870. Epub 2020 Dec 23.

Clinical practice guidelines for the management of biliary tract cancers 2019: The 3rd English edition

Masato Nagino  1 , Satoshi Hirano  2 , Hideyuki Yoshitomi  3 , Taku Aoki  4 , Katsuhiko Uesaka  5 , Michiaki Unno  6 , Tomoki Ebata  7 , Masaru Konishi  8 , Keiji Sano  9 , Kazuaki Shimada  10 , Hiroaki Shimizu  11 , Ryota Higuchi  12 , Toshifumi Wakai  13 , Hiroyuki Isayama  14 , Takuji Okusaka  15 , Toshio Tsuyuguchi  16 , Yoshiki Hirooka  17 , Junji Furuse  18 , Hiroyuki Maguchi  19 , Kojiro Suzuki  20 , Hideya Yamazaki  21 , Hiroshi Kijima  22 , Akio Yanagisawa  23 , Masahiro Yoshida  24 , Yukihiro Yokoyama  7 , Takashi Mizuno  7 , Itaru Endo  25
Affiliations
Practice Guideline

Clinical practice guidelines for the management of biliary tract cancers 2019: The 3rd English edition

Masato Nagino et al. J Hepatobiliary Pancreat Sci. 2021 Jan.

Abstract

Background: The Japanese Society of Hepato-Biliary-Pancreatic Surgery launched the clinical practice guidelines for the management of biliary tract cancers (cholangiocarcinoma, gallbladder cancer, and ampullary cancer) in 2007, then published the 2nd version in 2014.

Methods: In this 3rd version, clinical questions (CQs) were proposed on six topics. The recommendation, grade for recommendation, and statement for each CQ were discussed and finalized by an evidence-based approach. Recommendations were graded as Grade 1 (strong) or Grade 2 (weak) according to the concepts of the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) system.

Results: The 31 CQs covered the six topics: (a) prophylactic treatment, (b) diagnosis, (c) biliary drainage, (d) surgical treatment, (e) chemotherapy, and (f) radiation therapy. In the 31 CQs, 14 recommendations were rated strong and 14 recommendations weak. The remaining three CQs had no recommendation. Each CQ includes a statement of how the recommendations were graded.

Conclusions: This latest guideline provides recommendations for important clinical aspects based on evidence. Future collaboration with the cancer registry will be key for assessing the guidelines and establishing new evidence.

Keywords: biliary tract cancer; clinical practice; guideline.

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References

REFERENCES

    1. Takada T. Clinical practice guidelines for the management of biliary tract and ampullary carcinomas. J Hepatobiliary Pancreat Surg. 2008;15:1.
    1. Takada T, Miyazaki M, Miyakawa S, Tsukada K, Nagino M, Kondo S, et al. Purpose, use, and preparation of clinical practice guidelines for the management of biliary tract and ampullary carcinomas. J Hepatobiliary Pancreat Surg. 2008;15:2-6.
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    1. Nagino M, Takada T, Miyazaki M, Miyakawa S, Tsukada K, Kondo S, et al. Preoperative biliary drainage for biliary tract and ampullary carcinomas. J Hepatobiliary Pancreat Surg. 2008;15:25-30.

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