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Comment
. 2021 Jan:197:202-204.
doi: 10.1016/j.thromres.2020.10.038. Epub 2020 Nov 6.

Major cardiovascular events in patients with Coronavirus Disease 2019: Experience of a cardiovascular department of Northern Italy

Raffaello Bellosta  1 , Matteo Alberto Pegorer  2 , Luca Bettari  2 , Luca Luzzani  2 , Luca Attisani  2 , Alessandro Fossati  2 , Letizia Consoli  3 , Diego Maffeo  2 , Claudio Cuccia  2 , Paolo Terragnoli  3 , Ruth L Bush  4 , Gabriele Piffaretti  5
Affiliations
Comment

Major cardiovascular events in patients with Coronavirus Disease 2019: Experience of a cardiovascular department of Northern Italy

Raffaello Bellosta et al. Thromb Res. 2021 Jan.

Abstract

  1. •

    We report a translational experience of a cardiovascular department facing MACE in COVID-19 patients.

  2. •

    Acute arterial events are the real emergency into this COVID-19 pandemic.

  3. •

    COVID-19 infection may trigger a hypercoagulable status leading to MACE and high mortality rate.

  4. •

    In this COVID-19 outbreak, the adjunct of heparin provides better survival chance independently of the infection-related drug treatment.

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Conflict of interest statement

The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Figures

Fig. 1
Fig. 1
Number of MACE cases and the overall cohort of patients stratified by COVID-19 infection and department‘s unit.(MACE = Major Adverse Cardiovascular Events; CV19 = COVID-19)
Fig. 2
Fig. 2
Comparison of 2019 and 2020 including the estimated overall number of patients managed at the cardiovascular department, and the comparisons stratified by underlying cardiovacsular disease. (PE = pulmonary embolism; ACS = acute cardiac syndrome; ALI = acute limb ischemia).
See this image and copyright information in PMC

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References

    1. Guan W.J., Ni Z.Y., Hu Y., Liang W.H., Ou C.Q., He J.X., China Medical Treatment Expert Group for Covid-19 Clinical characteristics of coronavirus disease 2019 in China. N. Engl. J. Med. 2020;382:1708–1720. - PMC - PubMed
    1. Tang N., Bai H., Chen X., Gong J., Li D., Sun Z. Anticoagulant treatment is associated with decreased mortality in severe coronavirus disease 2019 patients with coagulopathy. J. Thromb. Haemost. 2020;18:1094–1099. - PMC - PubMed
    1. Hendren N.S., Drazner M.H., Bozkurt B., Cooper L.T., Jr. Description and proposed management of the acute COVID-19 cardiovascular syndrome. Circulation. 2020;141:1903–1914. - PMC - PubMed
    1. Shi S., Qin M., Shen B., Cai Y., Liu T., Yang F. Association of cardiac injury with mortality in hospitalized patients with COVID-19 in Wuhan, China. JAMA Cardiol. 2020 doi: 10.1001/jamacardio.2020.0950. - DOI - PMC - PubMed
    1. Lodigiani C., Iapichino G., Carenzo L., Cecconi M., Ferrazzi P., Sebastian T., Humanitas COVID-19 Task Force Venous and arterial thromboembolic complications in COVID-19 patients admitted to an academic hospital in Milan, Italy. Thromb. Res. 2020;191:9–14. - PMC - PubMed