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Review
. 2020 Nov 29;25(23):5621.
doi: 10.3390/molecules25235621.

Advances in the Chemical and Biological Characterization of Amaryllidaceae Alkaloids and Natural Analogues Isolated in the Last Decade

Marco Masi  1 , Roberta Di Lecce  1 , Alessio Cimmino  1 , Antonio Evidente  1
Affiliations
Review

Advances in the Chemical and Biological Characterization of Amaryllidaceae Alkaloids and Natural Analogues Isolated in the Last Decade

Marco Masi et al. Molecules. .

Abstract

Amaryllidaceae are bulbous wild and cultivated plants well known for their beautiful flowers and pharmaceutical applications, essentially due to the alkaloids and flavonoids content. Hundreds of alkaloids have been isolated until now and several scientific publications reported their sources, chemical structures, and biological activities. During the last decade, some unstudied Amaryllidaceae plants were the object of in-depth investigations to isolate and chemically and biologically characterize new and already known alkaloids as well as some analogues. This review describes the isolation and chemical and biological characterization of the Amaryllidaceae alkaloids, and their analogues obtained in the last decade, focusing the discussion on the new ones.

Keywords: Amaryllidaceae; alkaloids; last decade; natural analogues.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Alkaloids and natural analogues isolated from Phaedranassa dubia, Nerine huttoniae, Zephyranthes candida, Narcissus jonquilla quail, Lycoris longituba, Hippeastrum papilio, Nerine sarniensis, and Crinum latifolium.
Figure 2
Figure 2
Alkaloids isolated from Zephyrantes grandiflora, Brunsvigia natalensis, and Crinum jagus.
See this image and copyright information in PMC

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