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. 1977 Sep;17(3):541-5.
doi: 10.1128/iai.17.3.541-545.1977.

Microtiter solid-phase radioimmunoassay for detection of Escherichia coli heat-labile enterotoxin

H B Greenberg, D A Sack, W Rodriguez, R B Sack, R G Wyatt, A R Kalica, R L Horswood, R M Chanock, A Z Kapikian

Microtiter solid-phase radioimmunoassay for detection of Escherichia coli heat-labile enterotoxin

H B Greenberg et al. Infect Immun. 1977 Sep.

Abstract

The development of a microtiter solid-phase radioimmunoassay for the detection of Vibrio cholerae enterotoxin and heat-labile Escherichia coli enterotoxin is described. The test is based on the immunological similarity between V. cholerae toxin and E. coli heat-labile toxin. The assay is easy to perform, quantitative, and at least as sensitive and specific as the Y-1 adrenal cell system.

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