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. 2020;2(12):2509-2510.
doi: 10.1007/s42399-020-00657-7. Epub 2020 Nov 26.

Headache as a Prognostic Factor for COVID-19. Time to Re-evaluate

Paolo Martelletti  1   2 , Enrico Bentivegna  2 , Michelangelo Luciani  2 , Valerio Spuntarelli  2
Affiliations

Headache as a Prognostic Factor for COVID-19. Time to Re-evaluate

Paolo Martelletti et al. SN Compr Clin Med. 2020.

Abstract

Headache occurs in only about 13% of patients within the cohort of presenting COVID-19 symptoms. The hypothesis that such a painful symptomatic picture could be considered a prognostic factor for COVID-19 positive evolution or its trend of severity, or the co-generation of hyposmia/anosmia and/or hypogeusia/ageusia, needs robust epidemiological data, punctual pathophysiological demonstrations, and a detailed comparative analysis on drug-drug interactions (DDIs).

Keywords: COVID-19; Cytokine release syndrome (CRS); Drug–drug interactions (DDIs); Emergency medicine; Headache; Prognostic factors.

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Conflict of interest statement

Conflict of InterestThe authors declare that they have no conflict of interest.

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