Cell-mediated immunity to Nocardia asteroides induced by its ribonucleic acid protein fraction
- PMID: 332642
- PMCID: PMC421221
- DOI: 10.1128/iai.18.1.253-256.1977
Cell-mediated immunity to Nocardia asteroides induced by its ribonucleic acid protein fraction
Abstract
Guinea pigs immunized with ribonucleic acid protein fraction from Nocardia asteroides developed high cell-mediated immunity within 2 weeks, as shown by increased macrophage microbicidal activity and macrophage migration inhibition. This immunity protected against intravenous and subcutaneous challenge with N. asteroides and persisted for at least 70 days.
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