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Comment
. 2020 Dec;588(7837):209.
doi: 10.1038/d41586-020-03403-0.

Reversal of biological clock restores vision in old mice

Comment

Reversal of biological clock restores vision in old mice

Heidi Ledford. Nature. 2020 Dec.
No abstract available

Keywords: Ageing; Cell biology; Diseases; Epigenetics.

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Comment on

  • In Vivo Amelioration of Age-Associated Hallmarks by Partial Reprogramming.
    Ocampo A, Reddy P, Martinez-Redondo P, Platero-Luengo A, Hatanaka F, Hishida T, Li M, Lam D, Kurita M, Beyret E, Araoka T, Vazquez-Ferrer E, Donoso D, Roman JL, Xu J, Rodriguez Esteban C, Nuñez G, Nuñez Delicado E, Campistol JM, Guillen I, Guillen P, Izpisua Belmonte JC. Ocampo A, et al. Cell. 2016 Dec 15;167(7):1719-1733.e12. doi: 10.1016/j.cell.2016.11.052. Cell. 2016. PMID: 27984723 Free PMC article.
  • Reprogramming to recover youthful epigenetic information and restore vision.
    Lu Y, Brommer B, Tian X, Krishnan A, Meer M, Wang C, Vera DL, Zeng Q, Yu D, Bonkowski MS, Yang JH, Zhou S, Hoffmann EM, Karg MM, Schultz MB, Kane AE, Davidsohn N, Korobkina E, Chwalek K, Rajman LA, Church GM, Hochedlinger K, Gladyshev VN, Horvath S, Levine ME, Gregory-Ksander MS, Ksander BR, He Z, Sinclair DA. Lu Y, et al. Nature. 2020 Dec;588(7836):124-129. doi: 10.1038/s41586-020-2975-4. Epub 2020 Dec 2. Nature. 2020. PMID: 33268865 Free PMC article.

References

    1. Lu, Y. et al. Nature 588, 124–129 (2020). - DOI - PubMed - PMC
    1. Ocampo, A. et al. Cell 167, 1719–1733 (2016). - PubMed - DOI - PMC

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