Characteristics of Adults Aged 18-49 Years Without Underlying Conditions Hospitalized With Laboratory-Confirmed Coronavirus Disease 2019 in the United States: COVID-NET-March-August 2020

Daniel Owusu^{1

2}, Lindsay Kim^{1

3}, Alissa O'Halloran¹, Michael Whitaker¹, Alexandra M Piasecki^{1

4}, Arthur Reingold^{5

6}, Nisha B Alden⁷, Amber Maslar⁸, Evan J Anderson^{9

10}, Patricia A Ryan¹¹, Sue Kim¹², Kathryn Como-Sabetti¹³, Emily B Hancock¹⁴, Alison Muse¹⁵, Nancy M Bennett¹⁶, Laurie M Billing¹⁷, Melissa Sutton¹⁸, H Keipp Talbot¹⁹, Jake Ortega²⁰, Lynnette Brammer¹, Alicia M Fry^{1

3}, Aron J Hall¹, Shikha Garg^{1

3}; COVID-NET Surveillance Teama

Collaborators, Affiliations

Collaborators

COVID-NET Surveillance Teama:
Charisse N Cummings, Rachel Holstein, Anita Kambhampati, Seth Meador, Jonathan M Wortham, Shua J Chai, Breanna Kawasaki, Kimberly Yousey-Hindes, Kyle P Openo, Maya L Monroe, Libby Reeg, Ruth Lynfield, Nancy Eisenberg, Grant R Barney, Christina B Felsen, Jessica Shiltz, Nicole West, William Schaffner, Andrea Price

Affiliations

¹ CDC COVID-NET Team.
² Epidemic Intelligence Service, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
³ US Public Health Service, Rockville, Maryland, USA.
⁴ Cherokee Nation Assurance, Arlington, Virginia, USA.
⁵ California Emerging Infections Program, Oakland, California, USA.
⁶ School of Public Health, University of California, Berkeley, Berkeley, California, USA.
⁷ Colorado Department of Public Health and Environment, Denver, Colorado, USA.
⁸ Connecticut Emerging Infections Program, Yale School of Public Health, New Haven, Connecticut, USA.
⁹ Departments of Pediatrics and Medicine, Emory University School of Medicine, Atlanta, Georgia, USA.
¹⁰ Emerging Infections Program, Atlanta Veterans Affairs Medical Center, Atlanta, Georgia, USA.
¹¹ Maryland Department of Health, Baltimore, Maryland, USA.
¹² Michigan Department of Health and Human Services, Lansing, Michigan, USA.
¹³ Minnesota Department of Health, St. Paul, Minnesota, USA.
¹⁴ New Mexico Emerging Infections Program, Santa Fe, New Mexico, USA.
¹⁵ New York State Department of Health, Albany, New York, USA.
¹⁶ University of Rochester School of Medicine and Dentistry, Rochester, New York, USA.
¹⁷ Ohio Department of Health, Columbus, Ohio, USA.
¹⁸ Oregon Health Authority, Portland, Oregon, USA.
¹⁹ Vanderbilt University Medical Center, Nashville, Tennessee, USA.
²⁰ Salt Lake County Health Department, Salt Lake City, Utah, USA.

PMID: 33270136
PMCID: PMC7799269
DOI: 10.1093/cid/ciaa1806

Characteristics of Adults Aged 18-49 Years Without Underlying Conditions Hospitalized With Laboratory-Confirmed Coronavirus Disease 2019 in the United States: COVID-NET-March-August 2020

Daniel Owusu et al. Clin Infect Dis. 2021.

. 2021 Mar 1;72(5):e162-e166.

doi: 10.1093/cid/ciaa1806.

Authors

Collaborators

COVID-NET Surveillance Teama:
Charisse N Cummings, Rachel Holstein, Anita Kambhampati, Seth Meador, Jonathan M Wortham, Shua J Chai, Breanna Kawasaki, Kimberly Yousey-Hindes, Kyle P Openo, Maya L Monroe, Libby Reeg, Ruth Lynfield, Nancy Eisenberg, Grant R Barney, Christina B Felsen, Jessica Shiltz, Nicole West, William Schaffner, Andrea Price

Affiliations

¹ CDC COVID-NET Team.
² Epidemic Intelligence Service, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
³ US Public Health Service, Rockville, Maryland, USA.
⁴ Cherokee Nation Assurance, Arlington, Virginia, USA.
⁵ California Emerging Infections Program, Oakland, California, USA.
⁶ School of Public Health, University of California, Berkeley, Berkeley, California, USA.
⁷ Colorado Department of Public Health and Environment, Denver, Colorado, USA.
⁸ Connecticut Emerging Infections Program, Yale School of Public Health, New Haven, Connecticut, USA.
⁹ Departments of Pediatrics and Medicine, Emory University School of Medicine, Atlanta, Georgia, USA.
¹⁰ Emerging Infections Program, Atlanta Veterans Affairs Medical Center, Atlanta, Georgia, USA.
¹¹ Maryland Department of Health, Baltimore, Maryland, USA.
¹² Michigan Department of Health and Human Services, Lansing, Michigan, USA.
¹³ Minnesota Department of Health, St. Paul, Minnesota, USA.
¹⁴ New Mexico Emerging Infections Program, Santa Fe, New Mexico, USA.
¹⁵ New York State Department of Health, Albany, New York, USA.
¹⁶ University of Rochester School of Medicine and Dentistry, Rochester, New York, USA.
¹⁷ Ohio Department of Health, Columbus, Ohio, USA.
¹⁸ Oregon Health Authority, Portland, Oregon, USA.
¹⁹ Vanderbilt University Medical Center, Nashville, Tennessee, USA.
²⁰ Salt Lake County Health Department, Salt Lake City, Utah, USA.

PMID: 33270136
PMCID: PMC7799269
DOI: 10.1093/cid/ciaa1806

Abstract

Among 513 adults aged 18-49 years without underlying medical conditions hospitalized with coronavirus disease 2019 (COVID-19) during March 2020-August 2020, 22% were admitted to an intensive care unit, 10% required mechanical ventilation, and 3 patients died (0.6%). These data demonstrate that healthy younger adults can develop severe COVID-19.

Keywords: COVID-19; COVID-NET; SARS-CoV-2; hospitalization; young adults.

Published by Oxford University Press for the Infectious Diseases Society of America 2020.

PubMed Disclaimer

References

1. Wu Z, McGoogan JM. Characteristics of and important lessons from the coronavirus disease 2019 (COVID-19) outbreak in China: summary of a report of 72 314 cases from the Chinese Center for Disease Control and Prevention. JAMA 2020; 323:1239–42. - PubMed
1. Petrilli CM, Jones SA, Yang J, et al. Factors associated with hospital admission and critical illness among 5279 people with coronavirus disease 2019 in New York City: prospective cohort study. BMJ 2020; 369:m1966. - PMC - PubMed
1. Garg S, Kim L, Whitaker M, et al. Hospitalization rates and characteristics of patients hospitalized with laboratory-confirmed coronavirus disease 2019–COVID-NET, 14 states, March 1-30, 2020. MMWR Morb Mortal Wkly Rep 2020; 69:458–64. - PMC - PubMed
1. CDC. COVID-NET: Laboratory-confirmed COVID-19-associated hospitalizations [Internet]. 2020. Available at: https://gis.cdc.gov/grasp/COVIDNet/COVID19_3.html. Accessed 7 October 2020.
1. CDC. FluView interactive: laboratory-confirmed influenza hospitalizations [Internet]. 2020. Available at: https://gis.cdc.gov/GRASP/Fluview/FluHospRates.html. Accessed 8 October 2020.

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Characteristics of Adults Aged 18-49 Years Without Underlying Conditions Hospitalized With Laboratory-Confirmed Coronavirus Disease 2019 in the United States: COVID-NET-March-August 2020

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Characteristics of Adults Aged 18-49 Years Without Underlying Conditions Hospitalized With Laboratory-Confirmed Coronavirus Disease 2019 in the United States: COVID-NET-March-August 2020

Authors

Collaborators

Affiliations

Abstract

References

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MeSH terms

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Full Text Sources

Medical

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