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. 2020 Dec;25(48):2001813.
doi: 10.2807/1560-7917.ES.2020.25.48.2001813.

Association between SARS-CoV-2 infection and Kawasaki-like multisystem inflammatory syndrome: a retrospective matched case-control study, Paris, France, April to May 2020

Julie Toubiana  1   2 , Corinne Levy  3   4   5   6   7 , Slimane Allali  1 , Camille Jung  4   5 , Marianne Leruez-Ville  8 , Emmanuelle Varon  4   5   6   9 , Fanny Bajolle  10 , Naim Ouldali  11   3   6 , Judith Chareyre  12 , Stephane Béchet  3 , Annie Elbez  3   7 , Jean-Laurent Casanova  13   14 , Martin Chalumeau  1   15 , Robert Cohen  16   3   4   6   7 , Jérémie F Cohen  1   15
Affiliations

Association between SARS-CoV-2 infection and Kawasaki-like multisystem inflammatory syndrome: a retrospective matched case-control study, Paris, France, April to May 2020

Julie Toubiana et al. Euro Surveill. 2020 Dec.

Abstract

We assessed the association between severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and Kawasaki disease (KD)-like multisystem inflammatory syndrome in a retrospective case-control study in France. RT-PCR and serological tests revealed SARS-CoV-2 infection in 17/23 cases vs 11/102 controls (matched odds ratio: 26.4; 95% confidence interval: 6.0-116.9), indicating strong association between SARS-CoV-2 infection and KD-like illness. Clinicians should keep a high level of suspicion for KD-like illness during the COVID-19 pandemic.

Keywords: COVID-19; Kawasaki-like disease; MIS-C; PIMS-TS; SARS-CoV-2.

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Conflict of interest statement

Conflict of interest: ML has received travel grants to scientific meeting from Biomerieux and Abbott. All other authors report no potential conflicts.

Figures

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Figure
Flowchart of study participant selection
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References

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